Lower Extremity Wounds Treated with a Synthetic Hybrid-Scale Fiber Matrix

Introduction: Lower extremity wounds, including surgical wounds and chronic nonhealing wounds, are frequently difficult to treat. New treatment options are needed to improve healing. A synthetic biodegradable hybrid-scale fiber matrix* with an architecture similar to native tissue is gaining popularity due its effectiveness in treating various types wounds.

The present study was designed to evaluate the efficacy and utility of the synthetic hybrid-scale fiber matrix in the treatment of complex lower extremity wounds.

Methods: A retrospective analysis of 7 patients with a total of 7 wounds that underwent treatment utilizing the synthetic hybrid-scale fiber matrix was conducted. The wounds were treated with the synthetic matrix, wound healing progress was monitored, and the matrix was re-applied as needed.

Results: The average patient age was 62 years old. Patients’ co-morbidities included diabetes mellitus II, chronic kidney disease, peripheral artery disease, atrial fibrillation, and other co-morbidities. Treatment of the wounds with the synthetic matrix resulted in complete closure of all of the wounds over an average of 98 days with an average of 1.3 applications of Restrata.

Discussion and Conclusions: The synthetic hybrid-scale fiber matrix demonstrated high wound healing efficacy and only required a minimal number of applications. The successful outcomes suggest the utility of the synthetic hybrid-scale fiber matrix as a part of the wound care treatment paradigm.