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Poster CS-069

Study: a 21-DAY Stay-In-Place Dressing Wound Care System Utilizing Marine Extracts

Eric A Lewis, MD

Jennifer Nastanski, NP-C

Symposium on Advanced Wound Care Spring Spring 2022

Study: a 21-DAY Stay-In-Place Dressing Wound Care System Utilizing Marine ExtractsMOHS & deep shave excisions result in slow healing wounds in the elderly. A Dermatology Practice challenged conventional wisdom involving post-excisional care by implementing and studying a recently developed and tested OTC 21-day stay-in-place breathable liquid-permeable dressing in 70 patient procedures. This was compared to the current OTC dressing standard.

Methods: Post procedure, a Control Group (n=24) had an OTC dressing applied, with instructions to replace every other day, cleaning the site then applying a topical antibiotic. The Test Group (n=70), utilized the designed and engineered 21-day rayon dressing with marine extracts (sea cucumber & abalone) *. Test Group was instructed not to remove the dressing, while performing daily cleaning with water-soaked gauze. Speed of healing measured in healing time, mm2/day, and percent healing at 21 days were all statistically improved (p=0.001 - p=0.013) with the test dressing versus the control.

Conclusion: Historically, surgical and histopathological techniques have improved dramatically while wound dressings have changed minimally. Development and testing of a new 21-day stay-in-place dressing system utilizing marine extracts* resulted in faster healing, decreased effort and pain from dressing changes, and less scarring than traditional wound care. Minimization of wound stripping and reduction of surrounding skin disruption was noted, likely due to elimination of frequent adhesive dressing changes.

The dressing was also observed to reduce xerosis and micro-fissuring of the surrounding skin which are leading causes of inflammation, bacterial colonization and slow wound healing. Moreover, numerous studies have documented that marine extracts of sea cucumber and abalone stimulate and regulate collagen production in skin fibrocytes and have anti-inflammatory, antioxidant, and antimicrobial activity. *MBET-Health.com Miracle Dressing Wound Care System (MDS)

References

1. Se-Kwon Kim, Marine Nutraceuticals: Prospects and Perspectives. B CRC Press, 2013; 464 Pages. ISBN 978-1-4665-1351-82. Gerstein AD, Phillips TJ, Rogers GS, Gilchrest BA. Wound healing and aging. Dermatol Clin. 1993;11(4):749-757.3. Greenhalgh DG. Management of the skin and soft tissue in the geriatric surgical patient. Surg Clin North Am. 2015;95(1):103-114.4. Sen CK, Gordillo GM, Roy S, et al. Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen. 2009;17(6):763-771.5. Mazliadiyana M, Nazrun A, Isa N, Optimum Dose of Sea Cucumber (Stichopus Chloronotus) Extract for Wound Healing. Med & Health. 2017:12(1):83-896. Thaweekitphathanaphakdee S, Chanvorachote P, Prateepchinda S, Khongkow M, Sucontphunt A. Abalone Collagen Extracts Potentiate Stem Cell Properties of Human Epidermal Keratinocytes. Mar Drugs. 2019;17(7):424. Published 2019 Jul 20. doi:10.3390/md17070424

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