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Poster
1596481
Demographic Characteristics and Comorbidities of Patients With Narcolepsy: A Propensity Score–Matched Cohort Study
Psych Congress 2023
This study was funded by Avadel Pharmaceuticals.
Introduction: This is the first study to use aggregate electronic health record (EHR) data to characterize demographics and comorbidities of patients with narcolepsy.
Methods: An EHR-based search identified first-time Mayo Clinic patients between 2000–2020 who had ≥1 narcolepsy-specific ICD-9/10 code and ≥1 disease-supportive statement in clinical notes. A control cohort was propensity-matched and common comorbidities were compared between cohorts (odds ratio [OR]).
Results: In the EHR database (Nf6,389,186 patients), 2057 patients with narcolepsy (median age at first presentation to Mayo Clinic, 32 y [range, 17–48]; 59.6% female; 92.6% white; 89.2% non-Hispanic) were propensity-matched with a control cohort (n=2057; median age at first presentation to Mayo Clinic, 35 y [range, 12–52]; 58.9% female; 94.6% white; 84.5% non-Hispanic). Among comorbidities occurring more frequently in the narcolepsy cohort vs the control (OR [95% CI]; P
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