Fish skin xenografting post Mohs surgery on the lower extremities: a single institution experience

Introduction: Mohs surgery is a tissue-sparing dermatologic surgery utilized to treat skin cancers. Reconstruction of soft tissue defects following Mohs surgery can be challenging on the lower extremities due to limited adjacent tissue laxity and higher rates of post-operative infections[1]. Fish skin xenografts (FSX) from Atlantic cod (Gadus morhua)* are known to promote healing, reduce pain, & prevent infection in various wounds [2,3]. Herein we summarize our institutional experience with fish skin xenografting post-Mohs on the lower extremities to evaluate utility & efficacy.Methods:Retrospective case-series of 12 patients xenografted following Mohs surgery on the lower extremity from 5/2023 to 12/2023. Wounds were grafted within 2 weeks of surgery and re-grafted q2-4 weeks PRN. Re-grafting was performed when