Addressing Chronic Wound Bio Burden and Venous Insufficiency with Topical Antimicrobial Wound Gel within a Mobile Advanced Wound Management Program

Introduction: Wounds in patients with significant venous insufficiency and chronic stasis dermatitis may present complex challenges, often exacerbated by persistent bio burden. This study explores the effectiveness of antimicrobial wound gel* in managing a chronic wound following limited success with standard treatments and multiple forms of antibiotics.Methods:Following 34 visits to treat the wound on her lower right extremity utilizing standard care methods, including non-cytotoxic antibacterial foam, calcium alginate with silver, hydrophilic polyurethane matrix dressing, and a dual membrane dehydrated amnion graft, the wound has not improved. Cultures are taken regularly revealing persistent or worsening conditions due to excessive bio burden, often leading to cellulitis in and around her wound necessitating recurrent antibiotic treatments. Two-layer compressions and single layer Coban compressions are not tolerated, and the patient tends to roll applied a compression sleeve causing a bottleneck of her leg. Given these challenges, regular application of the antimicrobial wound gel was initiated. Weekly imaging and documentation in addition to regular cultures will continue.Results:The goal of this study is to understand the comparative effectiveness of the antimicrobial wound gel over previously utilized forms of antibiotics on reducing chronic bio burden and enhancing wound healing. Expected outcomes include a measurable improvement in the wound's condition and reduced incidence of recurrent infection.Discussion: By applying a topical solution to prevent future infection and continually assessing changes in the microbial environment, the result of this new treatment approach will be clear. The antimicrobial gel may provide improved management of wounds with significant bio burden in patients with severe venous insufficiency and chronic stasis dermatitis.References: