Psychologic Interventions Do Not Improve Biosimilar Confidence in Patients With Psoriasis

Results from a study published in Dermatology and Therapy found that psychologic interventions do not significantly alter the confidence of using biosimilars in patients with psoriasis.

Researchers aimed to assess the effectiveness of psychologic interventions on biosimilar confidence in a survey of a convenience sample of individuals with self-identified psoriasis. A total of 1285 subjects with self-reported psoriasis were randomized into 1 of 10 groups. Group A began with a hypothetical bio-originator and group B began with a hypothetical biosimilar. The remaining groups were provided with a hypothetical scenario where they switched to a biosimilar after achieving great results with a bio-originator and were randomized to receive various psychologic interventions.

No statistically significant differences were detected. However, illustrations implying comparability, explanations of the US Food and Drug Administration approval process, testimonials of treatment success in similar patients, and multiple-choice engagement and free response answers improved biosimilar confidence.

“Identifying highly impactful methods of improving biosimilar confidence remains a challenge,” concluded the study authors.

Reference
Hrin ML, Bray JK, Feldman SR. Reassurance techniques do not significantly impact confidence in biosimilars for psoriasis: a survey of a convenience sample of individuals with self-identified psoriasis. Dermatol Ther (Heidelb). Published online July 28, 2022. doi:10.1007/s13555-022-00781-3