July 2012 - FRMC

Tamoxifen Therapy for 10 Years versus 5 Years

07/22/2013

Chicago—Patients who took tamoxifen for 10 years had a reduced disease recurrence and breast cancer mortality compared with a group receiving the drug for 5 years, according to a randomized, phase 3 trial that began >20 years ago. The...

Chicago—Patients who took...

07/22/2013

First Report Managed Care

Novel Monoclonal Antibody to PCSK9

07/23/2012

Kevin L. Carter ;

Studies of animal models have found that proprotein convertase subtilisin/kexin 9 (PCSK9), one of the serine proteases, has a role in the post-translational regulation of LDL-receptor activity. PCSK9, which is synthesized primarily in the...

Studies of animal models have...

07/23/2012

First Report Managed Care

Bosutinib versus Imatinib in Treating Chronic Myeloid Leukemia

07/23/2012

Tim Casey ;

Chicago—After 30 months, patients with Philadelphia chromosome-positive chronic phase chronic myeloid leukemia who took bosutinib had superior efficacy and safety results compared with those who received imatinib, according to updated...

Chicago—After 30 months,...

07/23/2012

First Report Managed Care

Continuous Therapy in Prostate Cancer Patients

07/23/2012

Tim Casey ;

Chicago—A phase 3, international, randomized trial of patients with hormone-sensitive metastatic prostate cancer found that overall survival was inferior in those who had intermittent androgen deprivation therapy compared with those who...

Chicago—A phase 3,...

07/23/2012

First Report Managed Care

Orteronel to Treat Nonmetastatic Castration-Resistant Prostate Cancer

07/23/2012

Tim Casey ;

Chicago—An analysis of an ongoing phase 2 study found that patients with nonmetastatic, castration-resistant prostate cancer (nmCRPC) and rising prostate-specific antigen (PSA) reacted well to and managed toxicities when taking orteronel, an...

Chicago—An analysis of an...

07/23/2012

First Report Managed Care

T-DM1 Superior to Capecitabine plus Lapatinib in Advanced Breast Cancer

07/23/2012

Tim Casey ;

Chicago—The first phase 3 study to evaluate trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer found that the investigational antibody drug conjugate had superior efficacy and safety compared with an...

Chicago—The first phase 3 study...

07/23/2012

First Report Managed Care

Nab-Paclitaxel, Ixabepilone Not Superior to Paclitaxel

07/23/2012

Tim Casey ;

Chicago—A phase 3 study found that nab-paclitaxel and ixabepilone were not superior to standard treatment (paclitaxel) in patients with chemotherapy-naïve metastatic breast cancer who also received bevacizumab. Hope S. Rugo, MD, professor of...

Chicago—A phase 3 study found...

07/23/2012

First Report Managed Care

Afatinib Effective in Treating Late-Stage NSCLC

07/23/2012

Tim Casey ;

Chicago—Patients with advanced stage non–small cell lung cancer (NSCLC) who took the investigational oral agent afatinib had a significantly longer progression-free survival compared with those who received a standard combination chemotherapy...

Chicago—Patients with advanced...

07/23/2012

First Report Managed Care

Nausea and Vomiting in Cancer Patients

07/23/2012

Tim Casey ;

Orlando—When cancer patients undergo chemotherapy treatments, they face numerous challenges, among them nausea and vomiting. Physicians and nurses sometimes underestimate how many patients will have these side effects, according to Charles...

Orlando—When cancer patients...

07/23/2012

First Report Managed Care

News

Integrated Genetic Profiling in Acute Myeloid Leukemia

07/23/2012

Kevin L. Carter ;

A series of somatic mutations that affect the progression and development of acute myeloid leukemia (AML) has recently been discovered. The prognostic relevance of cytogenetic abnormalities has led to the widespread adoption of risk...

A series of somatic mutations...

07/23/2012

First Report Managed Care

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Statin Therapy Recipients Increase Under ACC/AHA Guidelines

04/22/2014

Melissa D. Cooper ;

A recent study showed statin therapy decreased relative cardiovascular risk by 25% [Database Syst Rev. 2013;1:CD004816]. In 2013, the American College of Cardiology and the American Heart Association (ACC/AHA) made recommendations for...

A recent study showed statin...

04/22/2014

First Report Managed Care

News

Health reform rule unveiled

07/12/2011

First Report Managed Care

News

CMS to Push Meaningful Use EHR Incentive Program to End of November

10/07/2014

The Centers for Medicare & Medicaid Services (CMS) has delayed the deadline for submitting meaningful use hardship exceptions for the electronic health records (EHRs) incentive program to November 30. The deadline was previously slated for...

The Centers for Medicare &...

10/07/2014

First Report Managed Care

News

2018 ACA Rates Likely to Vary Widely Across States

08/11/2017

Early rates for plans sold on the 2018 ACA individual market indicate that plan premiums will vary widely across the United States.

Early rates for plans sold on...

08/11/2017

First Report Managed Care

Interview

Using Clinical Natural Language Processing Solutions to Solve Payer Challenges, Improve Outcomes

05/18/2021

Frank Jackson, vice president and general manager of health language, Wolters Kluwer, emphasizes the importance of using the correct health language to improve processes for physicians and patients, as well as explains how to solve challenges...

Frank Jackson, vice president...

05/18/2021

First Report Managed Care

Video Insights

Videos

Bridging the Gaps in Prior Authorization: Challenges, Solutions, and Collaboration for Better Patient Care

11/13/2024

David Sand, MD, MBA, chief medical officer at ZeOmega, discusses the challenges of prior authorization, emphasizing the need for transparency, evidence-based standards, collaboration between payers and providers, and the potential for...

David Sand, MD, MBA, chief...

11/13/2024

First Report Managed Care

Videos

The Evolving Role of CGRP-targeting Therapies in Migraine Prevention

10/31/2024

Richard Lipton , MD;

Richard Lipton, MD, provides insights on the American Headache Society’s position statement update on calcitonin gene-related peptide (CGRP)-targeting therapies as a first-line option for the prevention of migraine.

Richard Lipton, MD, provides...

10/31/2024

First Report Managed Care

Videos

Unmet Needs in the Treatment and Management of Non–Small Cell Lung Cancer

09/26/2024

Alexander Spira , MD, PhD;

Alexander I. Spira, MD, PhD, discusses significant unmet needs in the treatment and management of non–small cell lung cancer (NSCLC).

Alexander I. Spira, MD, PhD,...

09/26/2024

First Report Managed Care

Videos

Treatment Options for NSCLC: A Discussion on Coverage, Clinical Outcomes, and Payer Perspectives

09/25/2024

Learn about research developments in 1L therapy for NSCLC patients with EGFR mutations and how outcomes may impact coverage and reimbursement decisions for insurers.

Learn about research...

09/25/2024

First Report Managed Care

Videos

Addressing the Root Cause of a Common Ocular Condition: A Virtual Roundtable

09/04/2024

View a roundtable discussion on Demodex blepharitis, a prevalent ocular condition that often goes undiagnosed in patients.

View a roundtable discussion on...

09/04/2024

First Report Managed Care

Videos

Addressing Health Disparities and Promoting Equity: The Role of Advanced Imaging Solutions

08/15/2024

Guest expert Jordan Bazinsky discusses the challenges facing the medical imaging industry, the potential of AI and emerging technologies, the role of advanced imaging solutions in promoting health equity, and the key trends and challenges...

Guest expert Jordan Bazinsky...

08/15/2024

First Report Managed Care

Videos

Promising Therapies and Clinical Trials for Chronic Lymphocytic Leukemia

08/14/2024

Farrukh T. Awan , MD;

Farrukh Awan, MD, highlights promising therapies and clinical trials within the field of chronic lymphocytic leukemia (CLL).

Farrukh Awan, MD, highlights...

08/14/2024

Journal of Clinical Pathways

Videos

Evolving Health Care Contact Centers Into Drivers of Value-Based Care

07/31/2024

Discover how health care contact centers can transform into drivers of value-based care through AI, automation, upskilling agents, and rethinking workflows and metrics to improve patient outcomes and population health.

Discover how health care contact...

07/31/2024

First Report Managed Care

Videos

Enhancing Patient Medication Adherence: Insights and Strategies From Asembia 2024

06/11/2024

Lucille Accetta, PharmD, MBA, MSPH, Senior Vice President of CVS Specialty Operations

Key stakeholders in the health care industry gathered to discuss prevalent topics at this year's Asembia annual summit. Medication adherence emerged as one of the most talked-about issues. In a session led by Lucille Accetta, PharmD, MBA,...

Key stakeholders in the health...

06/11/2024

First Report Managed Care

Melissa Andel, Principal, CommonHealth Solutions, LLC

Videos

Navigating the Impact of the Inflation Reduction Act: Implications for Payers, Patients, and Manufacturers

05/24/2024

Melissa Andel, Principal, CommonHealth Solutions, LLC

Learn about the impacts of the Inflation Reduction Act on payers and patients, highlighting the changes in Medicare benefits and drug coverage coming in 2025 and 2026.

July 2012 - FRMC

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