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New Therapies That Target the JAK-STAT Pathway and Other Small Molecules

08/08/2018

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Latest News

FDA alert
FDA Alert
FDA Approves Guselkumab for Moderate to Severe Ulcerative Colitis
09/12/2024
Johnson & Johnson’s guselkumab is the first and only fully-human, dual-acting monoclonal antibody that blocks IL-23 and binds to CD64.
Johnson & Johnson’s guselkumab is the first and only fully-human, dual-acting monoclonal antibody that blocks IL-23 and binds to CD64.
Johnson & Johnson’s guselkumab...
09/12/2024
Advances in Inflammatory Bowel Disease Network
News
Upadacitinib Provides Rapid Response in Crohn's Disease
08/29/2024
Pooled data from induction trials showed improvement in symptoms of Crohn’s disease within a week.
Pooled data from induction trials showed improvement in symptoms of Crohn’s disease within a week.
Pooled data from induction...
08/29/2024
Advances in Inflammatory Bowel Disease Network
News
Ustekinumab Shows Superior Persistence in CD Patients With Prior Biologic Use
08/26/2024
When used after a first-line agent, ustekinumab had significantly better persistence than other biologics.
When used after a first-line agent, ustekinumab had significantly better persistence than other biologics.
When used after a first-line...
08/26/2024
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
FDA Requires Warning Label Change for Thiopurines
08/13/2024
The agency stated that rare cases of intrahepatic cholestasis of pregnancy have been reported among pregnant patients treated with thiopurines for inflammatory bowel disease and systemtic lupus erythematosus.
The agency stated that rare cases of intrahepatic cholestasis of pregnancy have been reported among pregnant patients treated with thiopurines for inflammatory bowel disease and systemtic lupus erythematosus.
The agency stated that rare...
08/13/2024
Advances in Inflammatory Bowel Disease Network
News
MM-SES-CD and SES-CD Threshold Scores and Risk of Disease Progression
08/12/2024
Achieving multiplier Simple Endoscopic Score for Crohn’s Disease
Achieving multiplier Simple Endoscopic Score for Crohn’s Disease
Achieving multiplier Simple...
08/12/2024
Advances in Inflammatory Bowel Disease Network
News
Upadacitinib vs Tofacitinib for Clinical Remission in Ulcerative Colitis
08/09/2024
Investigators conducted a head-to-head trial of the 2 JAK inhibitors to determine which performed best in achieving steroid-free clinical remission among patients with ulcerative colitis
Investigators conducted a head-to-head trial of the 2 JAK inhibitors to determine which performed best in achieving steroid-free clinical remission among patients with ulcerative colitis
Investigators conducted a...
08/09/2024
Advances in Inflammatory Bowel Disease Network
News
Colorectal Cancer Risk Higher Among Patients WIth PSC, With or Without IBD
07/24/2024
Extended screening and surveillance are recommended for all patients with primary sclerosing cholangitis, but those with comorbid inflammatory bowel disease are at highest risk.
Extended screening and surveillance are recommended for all patients with primary sclerosing cholangitis, but those with comorbid inflammatory bowel disease are at highest risk.
Extended screening and...
07/24/2024
Gastroenterology
News
Biomarker Study Finds ‘Clearcut’ Case for Early Advanced Therapy for CD
05/24/2024

Jolynn Tumolo

Jolynn Tumolo
Top-down therapy significantly outperforms step-up treatment for Crohn’s disease with fewer adverse events.
Top-down therapy significantly outperforms step-up treatment for Crohn’s disease with fewer adverse events.
Top-down therapy significantly...
05/24/2024
Advances in Inflammatory Bowel Disease Network
fecal calprotectin test
News
Fecal Calprotectin: Effective Marker In Understanding Progression of Crohn's Disease
05/09/2024

Priyam Vora, Associate Editor

Priyam Vora, Associate Editor
Evidence shows the value of fecal calprotectin to better understand the trajectory of Crohn's disease.
Evidence shows the value of fecal calprotectin to better understand the trajectory of Crohn's disease.
Evidence shows the value of...
05/09/2024
Advances in Inflammatory Bowel Disease Network
News
Study Finds Higher-Than-Expected IBD Rates in US Black Women
05/02/2024

Jolynn Tumolo

Jolynn Tumolo
The incidence of inflammatory bowel disease was highest among Black women younger than 30 years of age.
The incidence of inflammatory bowel disease was highest among Black women younger than 30 years of age.
The incidence of inflammatory...
05/02/2024
Advances in Inflammatory Bowel Disease Network

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Latest Podcasts

IBD Drive time logo
Podcast
IBD Drive Time: David Hudesman, MD, on Work Productivity in IBD
09/19/2024
Dr David Hudesman of NYU-Langone Health joins IBD Drive Time host Dr Raymond Cross to talk about how inflammatory bowel disease affects work productivity and social activities.
Dr David Hudesman of NYU-Langone Health joins IBD Drive Time host Dr Raymond Cross to talk about how inflammatory bowel disease affects work productivity and social activities.
Dr David Hudesman of NYU-Langone...
09/19/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Erin Forster, MD, on Risankizumab for Ulcerative Colitis
09/03/2024
Dr Erin Forster of the Medical University of South Carolina joins IBD Drive Time hosts Dr Millie Long and Dr Raymond Cross to review results of the trials for risankizumab in ulcerative colitis and discuss its positioning in treatment.
Dr Erin Forster of the Medical University of South Carolina joins IBD Drive Time hosts Dr Millie Long and Dr Raymond Cross to review results of the trials for risankizumab in ulcerative colitis and discuss its positioning in treatment.
Dr Erin Forster of the Medical...
09/03/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Jordan Axelrad, MD, on IBD and Malignancy
08/19/2024
Dr Jordan Axelrad and host Dr Raymond Cross discuss the considerations for IBD treatment among patients with history of or a newly-diagnosed malignancy, including when to switch IBD treatments, the importance of controlling disease, and how...
Dr Jordan Axelrad and host Dr Raymond Cross discuss the considerations for IBD treatment among patients with history of or a newly-diagnosed malignancy, including when to switch IBD treatments, the importance of controlling disease, and how...
Dr Jordan Axelrad and host Dr...
08/19/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Dr Jana Al Hashash on Diet and Nutrition in IBD Care
08/05/2024
Dr Jana Al Hashash from Mayo Clinic—Florida offers guidance on how diet can affect IBD and the best approaches to maintaining adequate nutrition, along with hosts Millie Long, MD, and Raymond Cross, MD.
Dr Jana Al Hashash from Mayo Clinic—Florida offers guidance on how diet can affect IBD and the best approaches to maintaining adequate nutrition, along with hosts Millie Long, MD, and Raymond Cross, MD.
Dr Jana Al Hashash from Mayo...
08/05/2024
Advances in Inflammatory Bowel Disease Network
Shubha Bhat
Podcast
Shubha Bhat, PharmD, on the Role of the Clinical Pharmacist in IBD
07/25/2024
Dr Bhat reports on the recent systematic review and RAND consensus process to define the role of the clinical pharmacist in caring for patients with inflammatory bowel disease.
Dr Bhat reports on the recent systematic review and RAND consensus process to define the role of the clinical pharmacist in caring for patients with inflammatory bowel disease.
Dr Bhat reports on the recent...
07/25/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: The Best of DDW, Part 2
07/18/2024
In part 2 of this podcast, cohost Dr Millie Long discusses her picks for the "Best of DDW" on inflammatory bowel disease with her cohost, Dr Ray Cross.
In part 2 of this podcast, cohost Dr Millie Long discusses her picks for the "Best of DDW" on inflammatory bowel disease with her cohost, Dr Ray Cross.
In part 2 of this podcast,...
07/18/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Best of DDW, Part 1
07/09/2024
In the first episode of this two-part series, Dr Raymond Cross of Mercy Medical Center reviews his top picks for the best abstracts on inflammatory bowel disease presented at this year's Digestive Disease Week with cohost Dr Millie Long of...
In the first episode of this two-part series, Dr Raymond Cross of Mercy Medical Center reviews his top picks for the best abstracts on inflammatory bowel disease presented at this year's Digestive Disease Week with cohost Dr Millie Long of...
In the first episode of this...
07/09/2024
Advances in Inflammatory Bowel Disease Network
Millie Long
Video
Millie Long, MD, on Comparative Effectiveness in Ulcerative Colitis
06/24/2024
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation...
06/24/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: The Best of ECCO With Dr Frank Farraye
06/12/2024
Dr Frank Farraye, director of the IBD Center at Mayo Jacksonville, joins IBD Drive Time hosts Millie Long, MD, and Raymond Cross, MD, to review the best of presentations on the natural history of IBD at the European Crohn's & Colitis...
Dr Frank Farraye, director of the IBD Center at Mayo Jacksonville, joins IBD Drive Time hosts Millie Long, MD, and Raymond Cross, MD, to review the best of presentations on the natural history of IBD at the European Crohn's & Colitis...
Dr Frank Farraye, director of...
06/12/2024
Advances in Inflammatory Bowel Disease Network
Rishika Chugh
Podcast
Rishika Chugh, MD: Safety of Vedolizumab and Ustekinumab in Pregnancy
05/28/2024
Dr Chugh reviews the results of a recent study of the safety of ustekinumab and vedolizumab among pregnant patients with inflammatory bowel disease.
Dr Chugh reviews the results of a recent study of the safety of ustekinumab and vedolizumab among pregnant patients with inflammatory bowel disease.
Dr Chugh reviews the results of...
05/28/2024
Advances in Inflammatory Bowel Disease Network

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