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2022 Top 10
Deepak Bhatt, Editor-in-Chief, selects the 2022 Top 10
For Video Highlights, Click Here
See below for the most notable articles from JIC 2022
Practice Management
Differences in Short-Term Outcomes and Hospital-Based Resource Utilization Between Septal Reduction Strategies for Hypertrophic Obstructive Cardiomyopathy
Srikanth Yandrapalli, MD; Prakash Harikrishnan, MD; Gabriela Andries, MD; Wilbert S. Aronow, MD; Julio A. Panza, MD; Srihari S. Naidu, MD
Given clinical equipoise in a subset of obstructive hypertrophic cardiomyopathy (OHCM) patients who are candidates for both alcohol septal ablation (ASA) or septal myectomy (SM), other considerations such as cost, readmissions, and hospital length of stay (LOS) may be important to optimize healthcare resource utilization and inform shared decision making. In this retrospective observational analysis of the United States Nationwide Readmissions Database years 2012-2014, we identified adults who underwent isolated septal reduction for OHCM. We studied the differences in short-term outcomes and in-hospital resource utilization between the septal reduction strategies.
J INVASIVE CARDIOL 2022;34(1):E8-E13.
Covid-19 Pandemic/Practice Management
Invasive Management of Acute Myocardial Infarctions During the Initial Wave of the COVID-19 Pandemic
Nina Talmor, MD; Abhinay Ramachandran, MD, MS; Shari B. Brosnahan, MD; Binita Shah, MD, MS; Sripal Bangalore, MD, MHA; Louai Razzouk, MD, MPH; Michael Attubato, MD; Frederick Feit, MD; Craig Thompson, MD; Nathaniel R. Smilowitz, MD, MS
The initial wave of the coronavirus disease 2019 (COVID-19) pandemic resulted in an influx of patients with acute viral illness and profound changes in healthcare delivery in New York City. The impact of this pandemic on the presentation and in- vasive management of acute myocardial infarction is not well described. This single-center retrospective study compared pa- tients with myocardial infarction who underwent invasive coronary angiography at New York University from March-April 2020, during the peak of the first wave of the pandemic, with those presenting in March-April 2019.
J INVASIVE CARDIOL 2022;34(1):E32-E38.
Primary PCI
Frailty Among Patients With Acute ST-Elevation Myocardial Infarction in the United States: The Impact of the Primary Percutaneous Coronary Intervention on In-Hospital Outcomes
Josip A. Borovac, MD, PhD; Mohamed O. Mohamed, MBBCh, MRCP; Evangelos Kontopantelis, PhD; Mohamad Alkhouli, MD; M. Chadi Alraies, MD; Richard K. Cheng, MD, MS; Islam Y. Elgendy, MD; Poonam Velagapudi, MD, MS; Timir K. Paul, MD, PhD, MPH; Harriette G.C. Van Spall, MD, MPH; Mamas A. Mamas, BMBCh, DPhil, MRCP
This study sought to determine the average treatment effect of primary percutaneous coronary intervention PCI vs medical treatment on in-hospital outcomes across the spectrum of frailty in patients with ST-elevation myocardial infarction (STEMI). Adult patients hospitalized for STEMI between October 2015 until December 2017 from the National Inpatient Sample database were retrospectively analyzed and stratified by the Hospital Frailty Risk Score into low, intermediate, and high frailty risk subgroups. Propensity score matching analysis was performed to estimate the average treatment effect of primary PCI in each frailty subgroup. The primary outcome was all-cause in-hospital death.
J INVASIVE CARDIOL 2022;34(1):E55-E64.
Aortic Valve Disease
Valve-in-Valve Implantation of Medtronic CoreValve Prosthesis in Patients With Failing Bioprosthetic Aortic Valves: Mid-term Outcomes From the Italian Corevalve Clinical Service Project
Antonio Mangieri, MD; Arif A. Khokhar, BM, BCh; Anna Sonia Petronio, MD; Cristina Giannini, MD; Marco Angelillis, MD; Claudia Fiorina, MD; Marianna Adamo, MD; Salvatore Curello, MD; Corrado Tamburino, MD; Marco Barbanti, MD; Francesco Bedogni, MD; Luca Testa, MD; Alessandra Iadanza, MD; Massimo Fineschi, MD; Giuseppe Bruschi, MD; Arnaldo Poli, MD; Matteo Montorfano, MD; Diego Maffeo, MD; Antonio Colombo, MD
Valve-in-valve (ViV) TAVR is an emerging treatment option for failed surgical bioprosthesis. Choice of transcatheter valve is an important determinant of procedural and clinical outcomes, however, longer-term data are lacking. Our objective was to evaluate the acute and two-year safety and efficacy of using the Corevalve, Evolut R, and Evolut PRO valves for treating failed surgical bioprosthesis using data from the Italian CoreValve Clinical Service Project, a national clinical data repository evaluating the use of implantable devices across Italy. This multi-center analysis includes consecutive patients who underwent ViV-TAVR with the Medtronic CoreValve series between October 2008 to June 2019. Evaluated endpoints included rates of overall mortality, cardiovascular mortality, myocardial infarction, and cerebrovascular accidents at 2-year follow-up. Procedural success, complications, and echocardiographic outcomes were reported according to VARC-2 criteria.
J INVASIVE CARDIOL 2022;34(2):E73-E79.
Access Technique
The Transulnar Approach to Coronary Angiography and Intervention: Assessing the Anatomy of the Ulnar Artery Using Angiography
Nathan Kong, MD; Kiersten Rasberry; Daniel Gold, MD; Matthew Gold, MD; Linda Lee, MD; Joseph Kern, MD; Frank Medina, BS; Kiran Kaur, BS; Janet Friant, AP; Jonathan Paul, MD; Rohan Kalathiya, MD; Atman P. Shah, MD; Sandeep Nathan, MD; John Blair, MD
The transulnar approach has been proposed as a safe alternative to the more established transradial approach for cardiac catheterization. However, no study has assessed the anatomy and variability of the ulnar artery using angiography. A retrospective analysis of patients who underwent transradial cardiac catheterization during routine clinical care was conducted. Both quantitative and qualitative measurements of artery diameter were collected.
J INVASIVE CARDIOL 2022;34(3):E164-E170. Epub 2022 February 18.
High-Risk PCI
Cardiogenic Shock and Respiratory Failure Complicating Takotsubo Syndrome
Rohith Nayak, MD; Sarah Chiu, MD; Franz Schweis, MD; Albert Y.-J. Shen, MD, MS; Ming-Sum Lee, MD, PhD
The presentation of takotsubo syndrome mimics acute myocardial infarction. It is often diagnosed in the cardiac catheterization laboratory when no coronary obstruction is found. A subset of these patients develops shock or respiratory failure. This retrospective study aimed to evaluate the incidence, predictors, and outcomes of patients presenting to the cardiac catheterization laboratory with takotsubo syndrome complicated by respiratory failure or shock. These patients with takotsubo syndrome underwent cardiac catheterization at the Kaiser Permanente Southern California health system between 2006 to 2016. Medical records were manually reviewed to identify patient characteristics, treatment, and clinical outcomes.
J INVASIVE CARDIOL 2022;34(4):E274-E280.
Transcatheter Aortic Valve Replacement
Outcomes of Radial Versus Femoral Access in Patients With Severe Aortic Stenosis Undergoing Percutaneous Coronary Intervention Prior to Transcatheter Aortic Valve Replacement
Salman Farhat, MBBS; Abdallah El Sabbagh, MD; Mohammed Al-Hijji, MD; Keniel Pierre, MD; Nahyr S. Lugo-Fagundo, MD; Yader Sandoval, MD; Michael S. Gharacholou, MD; Peter M. Pollak, MD; Mandeep Singh, MD; Mackram F. Eleid, MD; Mohammed Al-Khouli, MD; David R. Holmes, MD; Mayra Guerrero, MD; Rajiv Gulati, MD; Malcolm Bell, MD; Charanjit S. Rihal, MD
The safety and feasibility of radial access in patients undergoing percutaneous coronary intervention (PCI) prior to transcatheter aortic valve replacement (TAVR) has not been studied. We included consecutive patients who underwent PCI within 30 days before TAVR at Mayo Clinic. Vascular access was left to the discretion of the operator. Baseline demographics, procedural data, PCI outcomes, and subsequent transfemoral TAVR outcomes were extracted from patient charts. A total of 331 patients were included in this study, with 107 patients undergoing PCI via radial access (rPCI), and 224 via femoral access (fPCI). Radial access for pre-TAVR PCI is feasible and safe and is associated with a lower rate of access-site hematoma. This study supports the increased use of transradial access for pre-TAVR PCI.
J INVASIVE CARDIOL 2022;34(5):E356-E362.
Peripheral Arterial Disease
Concomitant Drug-Coated Balloon Angioplasty With Bail-Out Use of Eluvia Drug-Eluting Stent: Is There Any Downside to a Double Dose of Paclitaxel?
Stefanos Giannopoulos, MD; Eric A. Secemsky, MD; Peter A. Schneider, MD; Ehrin J. Armstrong, MD
The application of 2 distinct and simultaneously applied drug-delivery platforms for the treatment of peripheral artery disease (PAD) has not been studied. Our objective was to investigate the outcomes of femoropopliteal disease treated with drug-coated balloon (DCB) followed by placement of drug-eluting stent (DES) when a bail-out procedure is required.
J INVASIVE CARDIOL 2022;34(6):E469-E476.
Coronary Artery Disease
Incidence, Treatment, and Outcomes of Coronary Artery Perforation During Percutaneous Coronary Intervention
Vennela Avula, BSPH; Judit Karacsonyi, MD, PhD; Spyridon Kostantinis, MD; Bahadir Simsek, MD; Bavana V. Rangan, BDS, MPH; Alessandra A. Gutierrez; M. Nicholas Burke, MD; Santiago Garcia, MD; Michael Mooney, MD; Paul Sorajja, MD; Jay H. Traverse, MD; Anil Poulose, MD; Ivan Chavez, MD; Yale Wang, MD; Mario Goessl, MD, PhD; Emmanouil S. Brilakis, MD, PhD
Coronary perforation is a potentially life-threatening complication of percutaneous coronary intervention. Our objective was to examine the incidence, treatment, and outcomes of perforation during percutaneous coronary intervention. We examined the clinical, angiographic, and procedural characteristics, management, and outcomes of coronary perforation at a tertiary-care institution.
J INVASIVE CARDIOL 2022;34(7):E499-E504. Epub 2022 June 17.
Coronary Imaging
3D Printing for Mesenteric Artery Endovascular Interventions: Feasibility and Utility for Preprocedural Planning and Angiographic Correlation
Sehrish Memon, MD; Evan Friend, MD; Sean Janzer, MD; Sanjog Kalra, MD; Jon C. George, MD
Three-dimensional (3D) printing of mesenteric artery (MA) anatomy preprocedurally for endovascular interventions can allow strategic preprocedure planning and improve procedure-related clinical outcomes. Three patients with computed tomography angiography (CTA) of the abdomen and pel- vis who subsequently underwent MA interventions were 3D printed retrospectively, and 2 patients with symptoms and severe MA stenosis on CTA, who had not undergone intervention, were 3D printed for procedure-related planning and anatomy-specific implications. The 3D-printed models were painted with acrylic paint to highlight anatomy. Reference vessel size, lesion length, and renal artery to MA distance were determined using a digital millimeter caliper.
