TMVR for Severe MR in a Down’s Syndrome Patient

Video supplement to ”Transcatheter Mitral Valve Repair for Severe Mitral Regurgitation in Down’s Syndrome,” by Hakeem, et al. (December 2021 Clinical Images).

This is the first published description of edge-to-edge transcatheter mitral valve repair (ETE-TMVr) in a patient with Down’s Syndrome. This case experience suggests a potential role for ETE-TMVr in high-risk and complex congenital mitral pathologies. This includes symptomatic Down’s Syndrome patients, particularly given the increasing life expectancy and reported high prevalence of regurgitant lesions in adults with trisomy 21.

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