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The 6-item Rapid Mood Screener outperformed the Mood Disorder Questionnaire in differentiating bipolar I disorder from major depressive disorder, according to a study published online in Current Medical Research and Opinion.

A new study finds that decreased activation of the LEF1 gene in patients with bipolar disorder (BD) could be a useful biomarker for lithium nonresponsiveness, streamlining treatment.

A meta-analysis has identified three-fold higher rates of major depression and generalized anxiety disorder among people with cannabis use disorder.

After losing a night’s sleep, people with high but subclinical attention-deficit/hyperactivity disorder (ADHD) traits performed worse on tasks involving attentional regulation and emotional control than people with low ADHD traits...

A stress-induced imbalance in gut microbiota led to depressive-like behaviors in mice, according to a study published in Nature Communications.

Depression, but not burnout, is directly linked with suicidal ideation in physicians, according to a study published online in JAMA Network Open.

The US Food and Drug Administration (FDA) has accepted Alkermes’ resubmission of the New Drug Application for ALKS 3831, a combination of olanzapine and samidorphan, the company announced.

Depressive symptoms, even at levels lower than thresholds used for depressive disorders, are associated with increased risk of incident cardiovascular disease, a study published in JAMA suggests.

In the early months of the COVID-19 pandemic, the proportion of people with clinically meaningful sleep difficulties grew to include half of all survey respondents, according to a study in the Journal of Sleep Research.

Psychedelic biotech firm MindMed announced the successful completion of a pre-investigational new drug (IND) meeting with the FDA on its development of LSD-assisted therapy for the treatment of an anxiety disorder. MindMed said it plans to...