Major Depressive Disorder: Monoamine Strategy vs Non-monoamine Strategy

This exciting event will feature a heated debate between two leading experts in the field of depression research, Dr Greg Mattingly and Dr Vladimir Maletic. Moderated by Dr Charles Raison, this debate will delve into the crucial question of whether depression is best understood as a neurotransmitter disorder, or a disorder of neural networks.

Be sure to watch the series of videos featuring each round of this engaging debate. Don’t forget to share your thoughts and tell us who you think won each round by answering the poll questions that appear on your screen!

Introduction

Monoamine Strategy vs Non-monoamine Strategy

In this debate moderated by Dr Charles Raison, watch as Dr Vladimir Maletic and Dr Greg Mattingly present their arguments for the optimal treatment approach for Major Depressive Disorder (MDD). Dr Maletic provides evidence in support of the non-monoamine strategy, while Dr Mattingly emphasizes the monoamine approach.

Round 1

Does speed matter?

In the first round, Dr Maletic and Dr Mattingly will debate whether major depressive disorder (MDD) is a brain disorder or a whole-body disorder. Both experts will present their opening arguments in a clear and concise manner, drawing on the latest research and their own experiences  in the field.

Round 2

Which clinical manifestations determine your approach?

In the second round, our speakers  will debate whether MDD is a neurotransmitter or neural network disorder, addressing specific issues related to the diagnosis and treatment of MDD. This will be an opportunity for the experts to strengthen their arguments and clarify their positions on key issues.

Round 3

Are inflammatory biomarkers sufficient indicators to strategize treatment for patients?

In the third round, the participants will debate as to which approach to MDD is more likely to produce effective treatments – the neurotransmitter modulation approach or the neural network modulation approach.

Closing Arguments

Debate Conclusion

The debate will conclude with closing arguments from each expert who will summarize their arguments and offer their final thoughts on the topic.

Don't miss this exciting opportunity to hear two leading voices  in the field of depression research engage in a lively and thought-provoking debate about the most effective way of understanding and treating MDD.