AUD Increases Mortality Risk for Cannabis Use Disorder Patients

Alcohol use disorder (AUD) has been shown to increase mortality risk among individuals with cannabis use disorder, according to a new study published online ahead of print by the journal Psychiatry Research.

The findings were based on a follow-up study of 1136 individuals in Northern Italy who had contacted health services regarding problems caused by cannabis use disorder between 2009 and 2019. The study excluded individuals who used opioids, amphetamines, cocaine, or injected drugs.

The researchers found that crude mortality rates were higher among study participants with cannabis use disorders and concomitant AUD compared to those with only cannabis use disorders. In terms of excess mortality with respect to the general population, standardized mortality rates were higher and statistically significant among patients with only cannabis use disorder as well as those with co-occurring AUD.

The researchers noted that while distinguishing cases in relation to alcohol use disorders allowed for more accurate estimates of the risk of death for individuals with cannabis use disorders, the role of tobacco remains unclear. Prior research has found the rate of tobacco smoking among people with cannabis use disorder is approximately 47%.

The researchers also noted that further studies are needed to analyze the effects of the COVID-19 pandemic on problematic consumption of cannabis and the associated risk of death.

Reference

Pavarin RM. Mortality risk for individuals with cannabis use disorders in relation to alcohol use disorders: Results of a follow-up study. Psychiatry Research. 2022. doi.org/10.1016/j.psychres.2022.114741