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The SHARP trial evaluated solriamfetol's effect on cognitive function in patients with obstructive sleep apnea (OSA) and excessive daytime sleepiness (EDS)-related cognitive impairment. T...
10/26/2023
Currently, there are no effective pharmacotherapies approved for experiential negative symptoms (ENS) of schizophrenia. Digital therapeutics (DTx) may represent a feasible option given ub...
10/26/2023

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Cognitive impairment is a major determinant of poor functional outcomes in schizophrenia. Currently, studies testing potential treatments for cognitive impairment have failed to demonstra...
10/26/2023
This analysis assessed the efficacy and safety of paliperidone palmitate 6-month (PP6M) in adults with schizophrenia who remained relapse free after a 1-year double-blind study (NCT033453...
10/26/2023
In a double-blind, randomized, parallel-group, active- and placebo-controlled, 14-day, dose-finding study in adult/elderly subjects with insomnia disorder, the 10 mg and 20 mg dose groups...
10/26/2023

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This post hoc analysis of a non-inferiority study (NCT03345342) found that adult patients with schizophrenia who transition to palmitate 6-month (PP6M) from either paliperidone palmitate ...
10/26/2023
Posttraumatic stress disorder (PTSD) is a serious neuropsychiatric illness for which novel treatment options are urgently needed. This multi-site, randomized, double-blind, confirmatory p...
10/26/2023
This post hoc analysis of a Phase 4, open-label, 8-week study evaluated if baseline clinical characteristics may influence the effect of adjunctive brexpiprazole on patient life engagemen...
10/26/2023

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We summarize clinical data on the effects of oxybates on sleep quality, sleep architecture, and disrupted nighttime sleep (DNS) in patients with narcolepsy. Key data from 4 studies on sod...
10/26/2023
This study explores the influence of race and sexual orientation on the stigma surrounding the treatment of GAD and MDD in a cohort of college students.
10/26/2023

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