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Posters

Effects of Aripiprazole Once-Monthly and Paliperidone Palmitate Once Monthly in Patients With Schizophrenia and Concomitant Substance Use: A Post-hoc Analysis of QUALIFY, a Head-to-Head Study

Background: Post-hoc analyses of the QUALIFY study (1), comparing effects of aripiprazole once-monthly (AOM 400) and paliperidone palmitate once-monthly (PP1M) treatment in patients with ...

Ross Baker , PhD, MBA;

Pedro Such , MD;

Jessica Madera , MD;

Simon Nitschky Schmidt , PhD;

Anna-Greta Nylander , PhD;

11/22/2019

Markov Chain Entropy Rate as an Adherence Volatility Metric

Introduction: Digital medicine consists of the marriage between active pharmaceuticals and wearable/ingestible sensors combined with mobile and web-based tools in the hope of improving th...

Zahra Heidary , PhD;

Jonathan Knights , PhD;

11/22/2019

A Randomized, Double-Blind, Placebo-Controlled Study of Delayed-Release and Extended-Release Methylphenidate in Children With ADHD: An Evaluation of Safety and Efficacy Throughout the Day and Across Settings

Purpose: Evening-dosed HLD200 is a delayed-release and extended-release methylphenidate (DR/ER-MPH) designed to provide treatment effect in the early morning, throughout the day, and into...

Andrew J. Cutler , MD;

Ann Childress , MD;

Andrea Marraffino , PhD;

Norberto DeSousa , MA;

Bev Incledon , PhD;

F. Randy Sallee , MD, PhD;

Sharon Wigal , PhD;

11/22/2019

Short- and Long-Term Metabolic Changes in Patients with MDD Treated with Adjunctive Brexpiprazole or Adjunctive Aripiprazole: An Indirect Comparison

Objective: We aimed to describe metabolic changes observed during short- and long-term studies of brexpiprazole and aripiprazole in patients with MDD.

Catherine Weiss , PhD;

Stine Rasmussen Meehan , PhD;

Peter Zhang , PhD;

Erin MacKenzie , PhD;

Francois Therrien , PharmD;

Ross Baker , PhD, MBA;

11/22/2019

Extended-Release Viloxazine (SPN-812) 200 mg or 400 mg for the Treatment of ADHD in Children: Topline Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study (P303)

Background: SPN-812 (extended-release viloxazine) is a structurally distinct, bicyclic, Serotonin Norepinephrine Modulating Agent (SNMA) being developed as a treatment for pediatric atten...

Stefan Schwabe , MD, PhD;

Azmi Nasser , PhD;

Joseph Hull , PhD;

Fatima Chowdhry , MD;

Toyin Adewole , MD, MPH;

Tesfaye Liranso , PhD;

11/22/2019

The Efficacy and Safety of Aripiprazole Once-Monthly 400mg (AOM 400) in African American/Black Patients Compared to Non-African American/Black Patients

Background: Recent analyses have indicated that medical treatment for schizophrenia varies among racial groups.

Jessica Madera , MD;

Stephen Murray , PharmD, MBA;

Maxine Chen , PhD;

Ross Baker , PhD, MBA;

Pedro Such , MD;

Cathy Zhao , PhD;

11/22/2019

Relationship Between ADHD Symptom and Executive Function Improvement in Adult ADHD in SHP465 Mixed Amphetamine Salts Extended-Release Clinical Trials

Adult attention-deficit/hyperactivity disorder (ADHD) is associated with impaired executive function (EF). This post hoc analysis examines relationships between changes in ADHD symptoms a...

Brigitte Robertson , MD;

Jie Chen , MS;

Thomas Brown , PhD;

11/22/2019

Frequency of Rehospitalization After Hospitalization for Suicidal Ideation or Suicidal Behavior in Patients With Depression

Background: Rehospitalization due to suicidal ideation (SI) or suicidal attempt (SA) could be used to measure effectiveness of depression treatments in patients at risk for suicide. There...

Jenna Reps , PhD;

Carla M. Canuso , MD;

M. Soledad Cepeda , MD, PhD;

Martijn Schuemie , PhD;

Dave Kern , PhD;

11/22/2019

Pooled Analysis From 12-Week Randomized, Controlled Studies of Solriamfetol in the Treatment of Excessive Daytime Sleepiness in Participants With Obstructive Sleep Apnea or Narcolepsy

Background: Solriamfetol (formerly JZP-110), a dopamine and norepinephrine reuptake inhibitor, has been approved in the US (SunosiTM) to improve wakefulness in adults with excessive dayti...

Colin Shapiro , PhD, FRCPC, MBBCh;

Michelle Baladi , PhD;

Dandan Chen , MD, PhD;

Helene Emsellem , MD;

Michael Thorpy , MD, CHBC;

Kris Liu , PhD;

Paula Schweitzer , MD, PhD;

Kimberly Babson , PhD;

11/22/2019

A Combination of Olanzapine and Samidorphan Has No Clinically Relevant Effect on QT Prolongation Up to Supratherapeutic Doses

Background: ALKS 3831, a combination of olanzapine and samidorphan (OLZ/SAM) in development for schizophrenia, is intended to mitigate olanzapine-associated weight gain. This thorough QT ...

Lisa L. von Moltke , MD, FCPP;

Lei Sun , PhD;

Sergey Yagoda , PhD, MD;

Hongqu Xue , PhD;

Randy Brown , MS;

Narinder Nangia , PhD;

Bhaskar Rege , PhD, BPharm;

Borje Darpo , MD, PhD;

David McDonnell , MD;

11/22/2019

NEW FROM THE NP INSTITUTE ONLINE LEARNING HUB

Rapid Refresh

Navigating Bipolar Disorder Treatment: Exploring the Role of Second-Generation Antipsychotics

04/11/2024

Featuring Andrew Penn, MS, PMHNP, and Julie Carbray, PhD, FPMHNP-BC, PMHCNS-BC, APRN

Featuring Andrew Penn, MS, PMHNP, and...

Andrew Penn, MS, PMHNP, and Julie Carbray, PhD, FPMHNP-BC, PMHCNS-BC, APRN, explore the nuanced role of second-generation antipsychotics in bipolar disorder treatment. They discuss the complexities of managing mania and depression phases and...

Andrew Penn, MS, PMHNP, and...

04/11/2024

Psych Congress NP Institute

Rapid Refresh

Long-Acting Injectables for Adolescents With Schizophrenia and Schizoaffective Disorder

04/10/2024

Amber Hoberg, PMHNP-BC, navigates the complexities of adolescent psychosis treatment, exploring the potential benefits and considerations of LAIs for schizophrenia and schizoaffective disorder, while emphasizing evidence-based practice for...

Amber Hoberg, PMHNP-BC,...

04/10/2024

Psych Congress NP Institute

Clinical Pearls

Tolerability Testing in Long-Acting Injectable Prescriptions

04/03/2024

Do clinicians need to test for tolerability before prescribing a long-acting injectable (LAI)? Desiree Matthews, PMHNP-BC, and Amber Hoberg, MSN, APRN, PMHNP-BC, offer their clinical insight.

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NEW FROM THE NP INSTITUTE ONLINE LEARNING HUB

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