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Abstract: Background Anhedonia, a key symptom of major depressive disorder (MDD), impacts patients' quality of life and treatment outcomes. However, limited research exists on healthcare ...
08/20/2024

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Abstract: Background: Deutetrabenazine is a vesicular monoamine transporter type 2 inhibitor for the treatment of adults with tardive dyskinesia (TD) and Huntington disease (HD)–related c...
08/20/2024
Abstract: Rationale No effective pharmacological treatments are available for cognitive impairments in schizophrenia. Iclepertin (BI 425809), a glycine transporter-1 inhibitor, enhances N...
08/20/2024
Abstract: This research analyzes the outcomes of a federal training grant first awarded in 2017 by the Health Resources and Services Administration (HRSA) to address the shortage of behav...
08/20/2024

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Abstract: Background: For patients with schizophrenia, long-acting injectable (LAI) antipsychotics can reduce relapse and hospitalization rates and improve adherence versus oral antipsych...
08/20/2024
Abstract: Introduction: A patient-digital therapeutic (DTx) bond (digital working alliance [DWA]) may be important for DTx success. We assessed whether patients with experiential negative...
08/20/2024
Abstract: Introduction: AXS-05 (dextromethorphan-bupropion; Auvelity) is a novel, oral, N-methyl-D-aspartate (NMDA) receptor antagonist and sigma-1 receptor agonist approved for treating ...
08/20/2024

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Abstract: Parkinson's Disease (PD) psychosis poses major treatment challenges due to the delicate balance required between managing motor deficits and psychotic symptoms. Treating PD asso...
08/20/2024
Abstract: Introduction: People with major depressive disorder (MDD) have impaired neuroplasticity. Antidepressant treatment and some nonpharmacological interventions can lead to changes i...
08/20/2024
Abstract: BACKGROUND: To generate real-world evidence of esketamine effectiveness for treatment resistant depression (TRD), this study assessed change in depressive symptoms after esketam...
08/20/2024

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