Impact of Comorbid Obesity on Psoriatic Arthritis (PsA) and Axial Spondyloarthritis (axSpA) Patient Outcomes

Assess your understanding of the impact of obesity on psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) patient outcomes. 

References

1. Kumthekar A, Ogdie A. Obesity and psoriatic arthritis: a narrative review. Rheumatol Ther. 2020;7(3):447-456. doi:10.1007/s40744-020-00215-6  

2. Maas F, Arends S, van der Veer E, et al. Obesity is common in axial spondyloarthritis and is associated with poor clinical outcome. J Rheumatol. 2016;43(2):383-387. doi:10.3899/jrheum.150648 

3. Maguire S, Wilson F, Gallagher P, O’Shea F. Central obesity in axial spondyloarthritis: the missing link to understanding worse outcomes in women? J Rheumatol. 2022;49(6):577-584. doi:10.3899/jrheum.211062 

4. Adult obesity facts. Centers for Disease Control and Prevention. Updated May 14, 2024. Accessed September 19, 2024. https://www.cdc.gov/obesity/php/data-research/adult-obesity-facts.html 

5. Gok K, Nas K, Tekeoglu I, et al. Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multicenter study. Rheumatol Int. 2022;42(4):659-668. doi:10.1007/s00296-021-04971-8 

6. Haugeberg G, Hoff M, Kavanaugh A, Michelsen B. Psoriatic arthritis: exploring the occurrence of sleep disturbances, fatigue, and depression and their correlates. Arthritis Res Ther. 2020;22(1):198. doi:10.1186/s13075-020-02294-w 

7. Leung YY, Eder L, Orbai AM, et al. Association between obesity and likelihood of remission or low disease activity status in psoriatic arthritis applying index-based and patient-based definitions of remission: a cross-sectional study. RMD Open. 2023;9(3):e003157. doi:10.1136/rmdopen-2023-003157 

8. Walsh JA, Wan MT, Willinger C, et al. Measuring outcomes in psoriatic arthritis: comparing Routine Assessment of Patient Index Data and Psoriatic Arthritis Impact of Disease. J Rheumatol. 2020;47(10):1496-1505. doi:10.3899/jrheum.190219  

9. Bindesbøll C, Garrido-Cumbrera M, Bakland G, Dagfinrud H. Obesity increases disease activity of Norwegian patients with axial spondyloarthritis: results from the European Map of Axial Spondyloarthritis Survey. Curr Rheumatol Rep. 2020;22(8):43. doi:10.1007/s11926-020-00917-4 

10. Liew JW, Huang IJ, Louden DN, Singh N, Gensler LS. Association of body mass index on disease activity in axial spondyloarthritis: systematic review and meta-analysis. RMD Open. 2020;6(1):e001225. doi:10.1136/rmdopen-2020-001225 

11. Cardena-de la Garza JA, Galarza-Delgado DA, Azpiri-Lopez JR, Colunga-Pedraza IJ, Guajardo-Jauregul N, Flores-Alvarado DE. Obesity is associated to higher nail psoriasis disease activity and prevalence in patients with psoriatic arthritis. Medical Dermatology Society. March 2022. Accessed September 12, 2024. https://www.meddermsociety.org/content/uploads/2022/03/Obesity-is-associated-to-higher-nail-psoriasis-disease-activity-and-prevalence-in-patients-with-psoriatic-arthritis-Cardenas-de-la-Garza.pdf 

12. Perez-Chada LM, Merola JF. Comorbidities associated with psoriatic arthritis: review and update. Clin Immunol. 2020;214:108397. doi:10.1016/j.clim.2020.108397