Importance of Holistic Management of Obesity in Psoriatic Arthritis (PsA) and Axial Spondyloarthritis (axSpA) Patient Populations

Take this quick quiz to deepen your understanding of the role holistic management plays in improving outcomes for psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) patients with obesity. 

References: 

1. Bosch P, Zhao SS, Nikiphorou E. The association between comorbidities and disease activity in spondyloarthritis - a narrative review. Best Pract Res Clin Rheumatol. 2023;37(3):101857. doi:10.1016/j.berh.2023.101857 

2. Singh S, Facciorusso A, Singh AG, et al. Obesity and response to anti-tumor necrosis factor-α agents in patients with select immune-mediated inflammatory diseases: a systematic review and meta-analysis. PLoS One. 2018;13(5):e0195123. doi:10.1371/journal.pone.0195123  

3. Campanholo CB, Maharaj AB, Corp N, et al. Management of psoriatic arthritis in patients with comorbidities: an updated literature review informing the 2021 GRAPPA treatment recommendations. J Rheumatol. 2023;50(3):426-432. doi:10.3899/jrheum.220310 

4. Kumthekar A, Ogdie A. Obesity and psoriatic arthritis: a narrative review. Rheumatol Ther. 2020;7(3):447-456. doi:10.1007/s40744-020-00215-6  

5. Guo Z, Yang Y, Liao Y, Shi Y, Zhang LJ. Emerging roles of adipose tissue in the pathogenesis of psoriasis and atopic dermatitis in obesity. JID Innov. 2022;2(1):100064. doi:10.1016/j.xjidi.2021.100064  

6. Porta S, Otero-Losada M, Kölliker Frers RA, Cosentino V, Kerzberg E, Capani F. Adipokines, cardiovascular risk, and therapeutic management in obesity and psoriatic arthritis. Front Immunol. 2021;11:590749. doi:10.3389/fimmu.2020.590749 

7. Klingberg E, Bilberg A, Björkman S, et al. Weight loss improves disease activity in patients with psoriatic arthritis and obesity: an interventional study. Arthritis Res Ther. 2019;21(1):17. doi:10.1186/s13075-019-1810-5