Incretin Levels May Predict Insulin Resistance Among Patients With Acne

Incretin may be used as a biomarker of insulin resistance in patients with acne vulgaris (AV), according to a recent study published in the Journal of Cosmetic Dermatology.

Researchers aimed to investigate the relationship between serum Incretin, AV, and insulin resistance, and to identify biological indicators of AV with insulin resistance. A total of 60 patients were included in the study wherein blood was tested for serum Incretin, blood lipids, sex hormones, and insulin release.

Incretin levels were lower in patients with AV who had insulin resistance compared to patients with AV without insulin resistance. Researchers also found that the insulin resistance index decreased as incretin level increased.

“Patients with acne vulgaris are prone to have insulin resistance. Insulin resistance in patients with acne vulgaris is negatively correlated with Incretin,” concluded the study authors. “Serum Incretin may be expected to be a biomarker for diagnosing acne vulgaris patients with insulin resistance,” they added.

Reference
Khattab FM, Fawzy M. Incretin serum level as a biomarker of insulin resistance in acne vulgaris patients. J Cosmet Dermatol. Published online: April 28, 2022. doi:10.1111/jocd.15025