Targeted Precision Cryotherapy Treatment for Acne Lesions

In a study published in Skin Research and Technology, researchers found that precision cryotherapy was shown to be an effective and safe treatment for acne vulgaris.

This pilot clinical trial investigated the feasibility and efficacy of precision cryotherapy as an alternative treatment for acne vulgaris, addressing the limitations and side effects associated with conventional therapies. A total of 20 volunteers underwent targeted precision cryotherapy using a carbon dioxide-based device. Treatment outcomes were evaluated through various parameters, including Investigator Global Assessment (IGA) scores, acne lesion counts, erythema index (EI), global evaluation scores, and participant satisfaction. Safety was monitored through adverse event reporting and physical examinations.

The results showed a significant reduction in acne lesions, with a 90.25% decrease in lesion count by week 4, accompanied by a marked improvement in IGA scores (P < 0.001). Additionally, the EI demonstrated notable improvements at weeks 1, 2, and 4. Clinical improvement, as measured by the global evaluation score, ranged from 75% to 100% by visit 4. Participants expressed high satisfaction with the procedure, with an average satisfaction score of 6.75 out of 7. Importantly, no adverse events or discomfort were reported throughout the study.

In conclusion, precision cryotherapy was shown to be an effective and safe treatment for acne vulgaris, leading to significant clinical improvement and high participant satisfaction. These findings suggest that precision cryotherapy holds promise as an alternative treatment option, particularly for patients with limited therapeutic choices. Further research is necessary to confirm these results and investigate the underlying mechanisms of action.

Reference
Hong JY, Kim KR, Kim HJ, Seok J, Park KY. Targeted precision cryotherapy for acne vulgaris. Skin Res Technol. 2024;30(9):e70045. doi:10.1111/srt.70045