Clinician’s Report: Antimicrobial Dressings

Covidien

Mansfield, MA • www.Covidien.com
(800) 438-0048 • KHPC-AMD@Covidien.com • Founded 1903

1) How many types or lines of antimicrobial dressings does your company currently make? There are two lines that make up the portfolio of AMD antimicrobial dressings. The AMD gauze based product line and the AMD foam based products.

2) What are some unique features of this product? The AMD family of products is unique as it is one of the only product families on the market utilizing Polyhexamethylene Biguanide (PHMB) as the antimicrobial. The PHMB in AMD antimicrobial products acts as a microbial barrier preventing microbes from penetrating through the dressing and inhibiting microbial growth within the dressings. The product is active whether it is wet or dry and does not delay wound healing. Simplicity is another key feature. For the product to work just take the product out of the package and apply it, as no activation is required.

3) What year was this product first created? The first AMD products were launched in 2001.

4) Is this product sold in bulk and if so what are the bulk amounts? The AMD family of products are not sold inbulk quantities at this time. However, Covidien welcomes opportunities and partnerships to meet the demands of clinicians.

5) Does the product come with a manufacturer’s warranty? No, there are no implied or stated warranties.

6) List any add on features that can come with this product. There are several products in the product portfolio including Kerlix™ AMD super sponges and rolls, Telfa™ AMD pads and Islands, Curity™ AMD gauze sponges, Curity™ AMD packing strips, Covidien Kendall AMD foam, Covidien Kendall™ AMD foam with top sheet, Covidien Kendall™ AMD foam fenestrated dressing, Covidien Kendall™ AMD foam fenestrated dressing with topsheet, as well as the Covidien Kendall™ AMD antimicrobial foam border dressings.

7) How does your product stand out from its competition? The AMD family of products is priced to allow everyone to utilize the dressings in a prophylactic approach. The dressings are cost effective enough to allow hospitals to apply the dressing to anyone that may be at risk for an infection. The dressings do not require any special handling; just use the dressings in the same manner as the standard non-impregnated dressings.

8) What is the MSRP price for this product? Pricing varies depending on the product size and type as well as local contract positions. However, the AMD portfolio of products is a cost effective solution where antimicrobial barrier products are needed.

9) Please list any important dimensions and measurements for this product. The AMD antimicrobial family of products comes in a variety of sizes designed to meet the needs of the most demanding customers.

10) Does this product come with any training services provided by your company or application instructions? There are no special training or instructions needed but there are product in-services available to help your staff understand the benefits of the AMD antimicrobial family of products.

11) How can prospective customers get more information on this product? Any customer can receive information on the AMD family of products at www.KendallAMD.com, www.KendallAMDfoam.com, and www.Covidien.com.

ConvaTec Inc.

Skillman, NJ • www.convatec.com
(800) 422-8811 or cic@convatec.com

Founded: ConvaTec has been providing advanced medical technologies for more than 30 years. In 2008, with backing from two private equity firms, ConvaTec became an independent enterprise.

1) How many types or lines of antimicrobial dressings does your company currently make? AQUACEL®Ag Hydrofiber®Wound Dressing with Ionic Silver comes in many sizes to fit a variety of wounds, including AQUACEL®Ag Ribbon with Strengthening Fibers. ConvaTec recently launched AQUACEL®Ag SURGICAL Cover Dressing for the post-operative care of surgical infections.

2) What is your best selling Antimicrobial Dressing? AQUACEL®Ag wound dressings with Hydrofiber®Technology.

3) What are some unique features of this product? AQUACEL®Ag dressings are soft, absorbent non-woven wound dressings based on Hydrofiber®Technology. They gel on contact with fluid, providing substantial wound care benefits. This unique gelling action enables the dressings to lock in exudate and its harmful components and contour closely to the wound bed. With the addition of ionic silver, AQUACEL®Ag dressing also provides “on demand” broad-spectrum antimicrobial activity. For incisions that are infected or at risk of infection, AQUACEL®Ag dressing provides rapid and sustained antimicrobial activity, killing a broad spectrum of pathogens within 30 minutes of exposure to the dressing, for up to 7 days, as demonstrated in vitro.

4) What year was this product first created? 1996

5) Is this product sold in bulk and if so what are the bulk amounts? AQUACEL®Ag dressing are sold in boxes of 5-10 dressings each.

6) Does the product come with a manufacturer’s warranty? We do not offer a manufacturer’s warranty with these products.

7) List any add on features that can come with this product. AQUACEL®Ag dressings contain ionic silver that has been shown in vitro to kill several strains of highly-resistant bacteria, commonly referred to as ‘Superbugs.’ The dressing was shown to kill ESBL-producing bacteria, A. baumannii, C. difficile and MRSA, including community-acquired MRSA.

8) How does your product stand out from its competition? AQUACEL®Ag dressings are soft, absorbent non-woven wound dressings based on Hydrofiber®Technology. They gel on contact with fluid, providing substantial wound care benefits. AQUACEL®Ag dressings are the only dressings with Hydrofiber® Technology available in a variety of shapes and sizes to meet specific wound needs. The AQUACEL®Ag Ribbon is made specifically for abscesses and the strengthening fibers allow for non-traumatic removal and less patient pain. AQUACEL®Ag SURGICAL provides a waterproof, viral and bacterial barrier that allows for flexibility and extensibility during movement and showed significant reduction in the incidence of SSI, skin blistering and delayed discharge.

9) What is the MSRP price for this product? Due to the various contracted prices for these products, we do not have an MSRP price for this line of products.

10) Please list any important dimensions and measurements for this product. AQUACEL®Ag dressings come in various sizes and types of flat sheets from 2”x2” to 8”x12”, and the ribbon dressing in 0.39” or 0.75” x18”. AQUACEL®Ag SURGICAL dressings are available in sizes from 3.5”x4” to 3.5”x14”.

11) Does this product come with any training services provided by your company or application instructions? Customers can contact their ConvaTec sales representative with any questions regarding our AQUACEL®Ag dressings. They can also contact our Customer Interaction Center at (800) 422-8811 and speak with a registered WOCN. Customers outside of the U.S. can visit www.convatec.com and select a specific location.

12) How can prospective customers get more information on this product? Customers in the U.S. can call our Customer Interaction Center at (800) 422-8811. Customers outside of the U.S. can visit www.convatec.com and select a specific location.

Molnlycke Health Care

US Headquarters: Norcross, GA. Global Headquarters: Gothenburg, Sweden
www.molnlycke.us • (800) 882-4582 or info.woundcare@molnlycke.com

1) How many types or lines of antimicrobial dressings does your company currently make? Molnlycke Health care offers 3 different antimicrobial dressings to meet the needs of various wound types: Mepilex® Ag antimicrobial foam dressing with Safetac® technology; Mepilex® Border Ag antimicrobial bordered foam dressing with Safetac® technology; Melgisorb® Ag antimicrobial calcium alginate dressing.

2) What is your best selling Antimicrobial Dressing? Mepilex® Ag antimicrobial foam dressing with Safetac® technology.

3) What are some unique features of this product? Mepilex® Ag is an antimicrobial foam product that minimizes pain and trauma at dressing changes thanks to the Safetac® technology adhesive. The dressings stays in place allowing easy application of compression or retention bandages and may be cut to suit various wound shapes and difficult-to-dress locations. Mepilex® Ag promotes patient comfort during wear, may remain in place for several days depending on the condition of the wound, and may be lifted and adjusted without losing its adherent properties. It has a low potential for skin irritation and allergy, and may be used on a variety of moderately exuding wounds.

4) What year was this product first created? 2006

5) Is this product sold in bulk and if so what are the bulk amounts? No

6) Does the product come with a manufacturer’s warranty? Yes

7) List any add on features that can come with this product. Mepilex® Ag offers a unique combination of powerful silver performance and gentle fixation with Safetac® technology. It offers immediate, sustained and effective antimicrobial protection to lower bacterial burden and minimize discomfort to the patient. Mepilex® Ag is flexible and highly conformable which helps with range of motion and rehabilitation. If a shower proof dressing is needed, we also offer Mepilex® Border Ag, which is available in standard, post-op and sacrum sizes.

8) How does your product stand out from its competition? Mepilex® Ag is a soft and highly conformable antimicrobial foam dressing that absorbs exudate and maintains a moist wound environment. The patented Safetac® technology (soft silicone) layer seals the wound edges, preventing the exudate from leaking onto the surrounding skin, thus minimizing the risk of maceration. The Safetac® layer ensures that the dressing can be changed without damaging the wound or surrounding skin or exposing the patient to additional pain. Mepilex® Ag inactivates wound related pathogens within 30 minutes with sustained effect up to 7 days. By reducing the number of microorganisms, Mepilex® Ag may also reduce odor. Products with Safetac® technology have been proven to help reduce skin blisters which may occur with traditional adhesives.

9) What is the MSRP price for this product? We do not make recommendations for retail pricing.

10) Please list any important dimensions and measurements for this product. Mepilex® Ag is available in a variety of sizes to address many different size wounds. Sizes include 4”x 4”, 4” x 8”, 6” x 6”, 8” x 8”, 8” x 20”, and 6” x 8.8” (Heel).

11) Does this product come with any training services provided by your company or application instructions? Yes, the dressing comes with application instructions in the packaging and instructions are available on product literature. Advanced application techniques are also available for partial thickness burns, donor sites and hand injuries. Molnlycke Health Care representatives offer inservicing and product education.

12) How can prospective customers get more information on this product? Call or email Customer Service at (800) 882-4582 or info.woundcare@molnlycke.com to contact your local representative who will provide all product information, clinical evidence and evaluation product.

Derma Sciences

Princeton, NJ • www.dermasciences.com
(800) 825-4325 or cs@dermasciences.com • Founded 1984

1) How many types or lines of antimicrobial dressings does your company currently make? BIOGUARD and ALGICELL Ag are two antimicrobial dressings in our full advanced wound care portfolio. BIOGUARD® Barrier Dressing is a best-in-class cationic biocide designed for prophylactic infection management and control on acute and chronic wounds. ALGICELL® Ag is a silver calcium alginate dressing with a sophisticated ionic transfer technology, superior absorption, and an optimal gelling profile. ALGICELL Ag provides an effective barrier to bacterial penetration and protects the wound against bacterial colonization.

2) What is your best selling Antimicrobial Dressing? Since it came to the market in 2010, our cationic biocide BIOGUARD Barrier Dressings has quickly gained acceptance with healthcare professionals. Prophylactic antimicrobial or anti-infective products are poised to have positive growth potential in the healthcare marketplace as MRSA and other resistant strains are a continued and growing concern. Surgical Site Infections now top 500,000 cases annually – and MRSA infections cause more deaths each year than HIV/AIDS.

3) What are some unique features of this product? BIOGUARD® Barrier Dressings have been proven to prevent bacterial penetration and inhibit growth within the dressing. The cationic biocide in BIOGUARD – polyDADMAC (poly diallyly dimethyl ammonium chloride) - is intrinsically bound to the dressing making it non-leaching and non-toxic to healthy cells. polyDADMAC ions have a very high charge density, which physically disrupts the cell structure of a pathogen, destroying it and rendering it unable foster bacterial resistance. The product is effective against a broad spectrum of pathogens.

4) What year was this product first created? After being featured in Time Magazine’s 2006 annual “Innovators” issue for its “Novel Intrinsically Micro Bonded Utility Substrate” (NIMBUS), Derma Sciences launched BIOGUARD to the wound care market in 2009.

5) Is this product sold in bulk and if so what are the bulk amounts? See Table 1.

6) Does this product come with any training services provided by your company or application instructions? No.

7) List any add on features that can come with this product. BIOGUARD® Barrier Dressings feature a novel cationic biocide that is significantly larger than other cationic biocides on the market. This relative increase in size helps PolyDADMAC to retain its biocidal activityafter repeated exposure and in the presence of wound fluid and other common wound products such as Dakins Solution and Santyl, demonstrating a consistent efficacy of >99.9% log kill.

8) How does your product stand out from its competition? Due to a patented manufacturing process, the active component within BIOGUARD® Barrier Dressings is intrinsically bound to the substrate – making it non-leaching. This is important as leaching antimicrobials can be toxic to good cells. BIOGUARD® is the only non-leaching dressing of its kind. Additionally, because of BIOGUARD’s active components’ relatively large size, bacteria can not develop resistance to BIOGUARD®. This is a vital benefit of a dressing being considered for prophylactic widespread usage. BIOGUARD® Barrier Dressings offer clinicians a truly unique, cost-effective and ideal line of barrier dressings that can play an important role in a facility’s infection protection program.

9) What is the MSRP price for this product? BIOGUARD is very cost-effectively priced for use as barrier dressing. The pricing varies by product configuration and size.

10) Does this product come with any training services provided by your company or application instructions? At Derma Sciences, we strive to deliver strong clinical support so that you have the confidence to use our broad product line appropriately and achieve consistent positive clinical outcomes.

  Towards that goal, our sales representatives and clinical field specialists provide in-depth and personal clinical assistance; we have an eLearning portal, available 24/7, designed to provide clinicians with valuable educational programs, educational product videos, extensive product literature, and protocol management tools; and a well established customer service center available to answer any questions.

11) How can prospective customers get more information on this product? Call a Derma Sciences Sales Representative, go to www.dermascience.com or call our customer service center at (800) 825-4325.

Systagenix

Quincy, MA • www.systagenix.com
(866) 978-3296 • customercareus@systagenix.com

1) How many types or lines of antimicrobial dressings does your company currently make? Systagenix has 4 lines of antimicrobial dressings: SILVERCEL® NON-ADHERENT, SILVERCEL®, ACTISORB® Silver 220 and PROMOGRAN PRISMA®, a collagen/ORC wound closing dressing that contains 1% silver for background antimicrobial effect.

2) What is your best selling Antimicrobial Dressing? SILVERCEL® NON-ADHERENT

3) What are some unique features of this product? SILVERCEL® NON-ADHERENT is the next generation of Silver Antimicrobial Dressing with the unique features of a Non-Adherent layer to maximize protection of the wound bed particularly at dressing change. The EMA “Easylift®” film layer keeps the dressing simple and convenient to use, minimizing pain and trauma at dressing change for your patients.

4) What year was this product first created? 2009

5) Is this product sold in bulk and if so what are the bulk amounts? N/A

6) Does the product come with a manufacturer’s warranty? Yes, all products will have an expiration date printed on the box and will be safe to use within the stated expiration.

7) List any add on features that can come with this product. In addition to the non-adherent layer which maximizes protection of the wound bed, SILVERCEL® NON-ADHERENT has proven antimicrobial strength1 and proven sustained release of silver¹. Additionally, the optimally spaced perforations allow ‘free flow’ of exudate into the dressing and also ensures the dressing stays intact.

8) How does your product stand out from its competition? SILVERCEL® NON-ADHERENT is the only non-adherent dressing featuring the EasyLift® EMA layer. This means that it is up to 75% less adherent than competitive brands¹. It also has superior absorbency and wet tensile strength when compared to other silver contact layers¹. With SILVERCEL® NON-ADHERENT you get all this and the antimicrobial effect you would expect from a silver dressing.¹ Essentially you get everything you could want from a silver dressing, but with the peace of mind that dressing changes will be easier for the clinician and less painful for the patient.^2,3

9) What is the MSRP price for this product? SILVERCEL® NON-ADHERENT is supplied through distribution; therefore an MSRP is not applicable. SILVERCEL® NON-ADHERENT is generally priced well below the market leader, which combined with the proven clinical results and enhanced patient comfort, makes it the most compelling antimicrobial dressing choice.

10) Please list any important dimensions and measurements for this product. SILVERCEL® NON-ADHERENT comes in the following sizes: (see Table 2).

11) Does this product come with any training services provided by your company or application instructions? All product shipped from Systagenix will come with instructions for use within the packaging. Additionally, application instructions can be found on www.systagenix.com as well as in the Let’s Heal® Product Reference Guide. Product demonstrations and in-services as well as wound healing educational modules can be arranged by contacting Systagenix at (866) 978-3296.

12) How can prospective customers get more information on this product? By visiting www.systagenix.com or by phoning (866) 978-3296.

References

1. Rachael Clark PHD, Sally-Anne Stephens, Michelle Del Bono, Omotayo Abioye, Simon Bayliff. The Evaluation of Absorbent Silver containing dressings In Vitro. Poster presented at Wounds UK 2009.

2. Non-Adherent Properties of a New Antimicrobial Dressings Demonstrated by Clinical Evaluations. Snyder et al. Presented at Wounds UK, 2010.

3. Ivins, N. et al. A series of case studies using a silver non-adherent dressing. Poster, WIC 2011.