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HI-PEITHO: New Study to Address Disparate Clinical Guidelines in Treatment of Pulmonary Embolism
In this episode of VDM Voices, we discuss pulmonary embolisms (PE), the current treatment options and guidelines, as well as a new trial now enrolling called HI-PEITHO that looks to address some of the unmet needs that currently exist.
Our guest host is Dr. Michael Jaff, Chief Medical Officer & Vice President, Peripheral Interventions at Boston Scientific. He is joined by Stavros V. Konstantinides, the principal investigator of the HI-PEITHO study and a Professor for Clinical Trials and Medical Director of the Center for Thrombosis and Hemostasis (CTH) at the University of Mainz, Germany. He also serves as a Professor of Cardiology at the Democritus University of Thrace, Greece.
Stavros Konstantinides, MD, FESC, is Professor for Clinical Trials and Medical Director of the Center for Thrombosis and Hemostasis (CTH) at the University of Mainz, Germany. He is also Professor of Cardiology at the Democritus University of Thrace, Greece. He graduated from the Aristotle University of Thessalonica, Greece, and earned his doctorate degree at the University of Freiburg, Germany. For the past 30 years, his clinical and translational research has focused on the risk stratification and risk-adapted antithrombotic management of thrombosis and pulmonary embolism. He has designed and coordinated, and has been principal investigator of numerous high-impact national and international academically sponsored multicenter trials. He is leading member of national and European committees, task forces for clinical practice guidelines, and of networks on pulmonary circulation and right ventricular function.
Michael R. Jaff, DO, is the Chief Medical Officer and Vice-President of clinical affairs, technology and innovation at Boston Scientific Corporation. A professor of medicine at Harvard Medical School, Dr. Jaff was the President of Newton-Wellesley Hospital from October 2016-December 2019. Prior to that, Dr. Jaff was the inaugural Paul and Phyllis Fireman Endowed Chair of Vascular Medicine and Medical Director of the Fireman Vascular Center at the Massachusetts General Hospital. He is an expert in all aspects of vascular medicine, including peripheral artery disease, venous thromboembolic disease, aneurysmal diseases, and all diagnostic strategies in vascular medicine. He is the founder of VasCore, the Vascular Ultrasound Core Laboratory, the largest of its’ kind in the United States. VasCore has participated in trial design and independent analysis of vascular laboratory images for over 200 prospective multicenter peripheral vascular device and pharmaceutical trials across 66 countries. Dr. Jaff has published extensively in the field of Vascular Medicine with over 300 peer-reviewed publications and 10 textbooks, is the Past-President of the Society for Vascular Medicine and Biology and was the first physician to have received the designation as Master of the Society for Vascular Medicine. He is a Fellow of the American College of Physicians, American College of Cardiology, the American Heart Association, and the Society for Cardiovascular Angiography and Intervention, and is a registered physician in vascular interpretation (RPVI). In November 2011, Dr. Jaff became an alumnus of Harvard Business School after completing the General Management Program.
