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EscharEx - MediWound 

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00329-8/fulltext

Results of a 196-patient RCT comparing the efficacy of ExcharEx for debridement of VLUs vs placebo (GV) and nonsurgical SoC (NSSOC) showed a significantly higher incidence of complete debridement at 63% compared to GV (30.2%) and NSSOC (13%), without significant safety issues. The Lancet

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