Negative Pressure Wound Therapy

Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Section (GSUC)   This study is currently recruiting participants.   Summary: The purpose of this study is to compare how well two methods (VAC and GSUC) of securing skin grafts using negative pressure wound therapy work. Negative pressure wound therapy is a commonly used method of applying suction on wounds to remove fluid from the wound and to promote healing. The VAC system is widely used and consists of foam dressing and a portable computerized suction pump. The G-SUC method uses commonly available dressing supplies attached to a vacuum (suction) pump located on the wall above a hospital bed. Both methods have been observed by the investigators for the last 10 years with no observed side effects. By completing the trial, the researchers’ primary intention is to establish that G-SUC is not inferior to VAC, and that G-SUC is less expensive and can be applied to wounds that VAC cannot.   Location: University of Chicago Medical Center, Section of Plastic and Reconstructive Surgery, Chicago, Illinois   Sponsor: University of Chicago   Principle investigator: Lawrence J. Gottlieb, MD, University of Chicago, Section of Plastic and Reconstructive Surgery   Identifier: NCT00952120 Efficacy Study of a Bioelectric Dressing Used With Negative Pressure Wound Therapy to Treat Diabetic and Pressure Ulcers   This study is currently recruiting participants.   Summary: The purpose of this study is to determine whether a bioelectric wound dressing, used in conjunction with negative pressure wound therapy (NPWT), is effective in the treatment of diabetic and pressure ulcers of the foot. Primarily, the researchers would like to establish wound healing in the first three months of treatment, including pain reduction. The participants will be divided into two groups: the first group will undergo V.A.C. Therapy once a week; while Group 2 will receive V.A.C. Therapy and Procellera Wound Dressing once per week.   Location: Wyckoff Heights Medical Center, Brooklyn, New York   Sponsor: Vomaris Innovations   Principle investigator: Ronald M. Guberman, DPM, Wyckoff Heights Medical Center   Identifier: NCT01022216 Comparative Effectiveness Study of MIST Therapy Versus Negative Pressure Wound Therapy   This study is currently recruiting participants.   Summary: The purpose of this study is to evaluate the clinical and economic effectiveness of MIST Therapy vs NPWT vs MIST Therapy in conjunction with NPWT in the treatment of full thickness wounds presenting in the LTACH and SNF settings. This study will be comparative, prospective, and randomized. Over the course of 6 weeks, the investigators will primarily look at the change in the wound surface, and will also study the changes in wound exudation levels. Cost, adverse effects, and severity of wound pain will also be examined. Participants will be divided into three groups. Group 1 will receive MIST Therapy 3 times per week; Group 2 will be treated with VAC according to manufacturer’s guidelines; and Group 3 will receive both VAC (according to manufacturer’s guidelines) and MIST Therapy (3 times per week).   Location: Trillium Specialty Hospital, Mesa, Arizona   Sponsor: Celleration, Inc.   Principle investigator: Kenneth O. Anaeme, MD, Trillium Specialty Hospital   Identifier: NCT01200563   The information contained in this update was summarized from www.clinicaltrials.gov.    Copyright © US National Library of Medicine.