precision medicine

Quiz

08/25/2016

JCP Editors

A study published in Science Translational Medicine found that the inhabitation of what oncogenic protein might possibly be a target for therapeutic benefit in patients with non-small cell lung...

A...

08/25/2016

Journal of Clinical Pathways

Research in Review

New Lung Cancer Biomarker Identified

08/22/2016

JCP Editors

Inhibition of oncogenic protein BMI1 may offer a therapeutic benefit for certain patients with lung cancer, according to the results of an analysis published in Science Translational Medicine. In a prior study,...

...

08/22/2016

Journal of Clinical Pathways

Quiz

Friday Morning Quiz ‚Äì Week of August 15-21

08/18/2016

JCP Editors

A recent study of non-small cell lung cancer found that those with epidermal growth factor receptor (EGFR)-positive disease were at an increased likelihood of developing leptomeningeal metastases (LM), but that...

A...

08/18/2016

Journal of Clinical Pathways

Research in Review

ESR1 Mutations May Affect Treatment for Metastatic Breast Cancer

08/16/2016

JCP Editors

Estrogen receptor α (ESR1) mutations are highly prevalent in women receiving aromatase inhibitors for metastatic breast cancer (MBC), according to a secondary analysis from a clinical trial. ESR1 mutations found in...

...

08/16/2016

Journal of Clinical Pathways

Research in Review

Treatment Combination Improves NSCLC Survival and Response

08/12/2016

JCP Editors

East Asian patients with advanced nonsquamous non-small cell lung cancer (NSCLC) and epidermal growth factor receptor mutations may benefit from treatment with pemetrexed plus gefitinib, results from a phase II...

East...

08/12/2016

Journal of Clinical Pathways

Research in Review

Equivalent Outcomes With Two NSCLC Treatment Options

08/04/2016

JCP Editors

Erlotinib may be an effective therapeutic option for patients with pretreated advanced non-small cell lung cancer (NSCLC) and no known molecular alterations, according to a study published in the journal Lung...

...

08/04/2016

Journal of Clinical Pathways

Research in Review

Radiotherapy Use and Effectiveness in Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma

08/02/2016

JCP Editors

A study of adjuvant chemoradiotherapy (CRT) and boost doses of postoperative radiotherapy (B-PORT) in oropharyngeal squamous cell carcinoma (OSCC) has found that outcomes depend on a number of pathologic and...

...

08/02/2016

Journal of Clinical Pathways

Research in Review

Protein Predicts Prognosis in Gastric Cancer

08/02/2016

JCP Editors

The protein calpain-9 may be an independent factor for poor prognosis that, when combined with TNM stage, may provide a better predictive model for outcomes in patients with gastric cancer, according to a study...

The...

08/02/2016

Journal of Clinical Pathways

Research in Review

Vemurafenib Improves Response in Patients With Thyroid Cancer

07/28/2016

JCP Editors

Vemurafenib, a drug originally approved for use in patients with BRAF-positive melanoma, has also shown promising anti-tumor activity in some patients harboring this same mutation in thyroid cancer, according to the...

...

07/28/2016

Journal of Clinical Pathways

Research in Review

Ipilimumab Combination Significantly Improves Melanoma Outcomes

07/27/2016

JCP Editors

Ipilimumab (Yervoy; Bristol-Myers Squibb) combined with local peripheral treatments such as radiotherapy or electrochemotherapy may significantly prolong survival in patients with melanoma compared with...

...

07/27/2016

Journal of Clinical Pathways