precision medicine

Research in Review

Multikinase Inhibitors Ineffective in Treating RET-Rearranged NSCLC

03/17/2017

JCP Editors

Overall response rate (ORR) is low for patients with non-small cell lung cancer (NSCLC) with RET rearrangements after targeted therapy, according to research published in the Journal of Clinical Oncology (March 13,...

...

03/17/2017

Journal of Clinical Pathways

Department

Genetic Counseling Implementation Plausible During Routine Follow-up Care

03/15/2017

JCP Editors

More than 70% of childhood cancer survivors receiving follow-up treatment expressed interest in meeting with genetic counselors to better understand cancer predisposition, according to a pilot study conducted at a...

More...

03/15/2017

Journal of Clinical Pathways

Research in Review

Genetic Mutations May Be Used as Biomarkers for Relapsing CLL

02/24/2017

JCP Editors

Mutations in the BTK and PLCG2 genes have the potential to be used as a biomarker for relapse of chronic lymphocytic leukemia (CLL) after treatment with ibrutinib, according to a retrospective review published in the...

...

02/24/2017

Journal of Clinical Pathways

Research in Review

Genomic Profiling, Targeted Therapy Effectively Treats Histiocytic Disorders

02/17/2017

JCP Editors

Genomic profiling should be applied to patients with histiocytic disorders at diagnosis in order to guide targeted therapy, according to research published in the Journal of Clinical Investigation Insight (February...

...

02/17/2017

Journal of Clinical Pathways

Department

Genomics of Estrogen Receptor-Positive Cancer Changes Following Metastasis

02/13/2017

JCP Editors

A genomic analysis revealed significant differences in the genomic landscape of estrogen receptor (ER)-positive metastatic breast cancers when compared with ER-positive primary tumors. These alterations frequently...

A...

02/13/2017

Journal of Clinical Pathways

Research in Review

Precision Medicine Approach Effective in Evaluating Pediatric Brain Tumors

01/20/2017

JCP Editors

A combination of genomic assays could be an effective precision medicine approach for clinical diagnosis, prognosis, and treatment guidance of pediatric brain tumors, according to new research published in...

A...

01/20/2017

Journal of Clinical Pathways

Research in Review

Precision Medicine Increasingly Guides Decision-Making for Patients with Breast Cancer

12/29/2016

JCP Editors

Breast cancer serves as a model for using precision medicine to guide treatment decisions and improve patients’ quality of life, according to a presentation at the 2016 Lynn Sage Breast Cancer...

Breast...

12/29/2016

Journal of Clinical Pathways

Quiz

Friday Morning Quiz: Week of October 16-22

10/20/2016

JCP Editors

A recent review of more than 10 years of published clinical data revealed that the use of what type of therapy in regimens for gastroenteropancreatic neuroendocrine tumors (GEPNETs) could improve outcomes, minimize...

A...

10/20/2016

Journal of Clinical Pathways

Research in Review

Novel, Low-Cost Method for Examining Leukemia Cells Developed

10/19/2016

JCP Editors

A group of Swedish researchers may have found a cost-efficient way of examining individual leukemia cells, which could transform treatment strategies and make care more personalized, according to a study published in...

A...

10/19/2016

Journal of Clinical Pathways

Research in Review

MicroRNA a Novel Biomarker for Gastric Cancer

10/12/2016

JCP Editors

Serum microRNA-206 (miRNA) may serve as not only a novel diagnostic biomarker for gastric cancer but also as an indicator of prognosis and cancer recurrence, according to a study published in Cellular Physiology and...

Serum...

10/12/2016

Journal of Clinical Pathways