Ivan Jozic

Inflammation is Induced by Intracellular MRSA Colonization of Diabetic Foot Ulcers

Background: Persistent wound infection frequently complicates diabetic foot ulcers (DFU) treatment and is a leading cause of amputations. Dramatic increase in community-acquired Methicill...

Robert S. Kirsner , MD, PhD;

Marjana Tomic-Canic , PhD;

Rivka Stone ;

Jamie Burgess , MS;

Hadar A. Lev-Tov , MD, MAS, MSc;

Cheyanne R. Head ;

Irena Pastar , PhD;

Andrew Sawaya ;

Ivan Jozic ;

Natasa Strbo , MD, PhD;

Jelena Marjanovic ;

08/19/2021

A scientific review of the chemistry of wound healing and hypochlorous acid, why purity of the molecule in a wound cleansing solution matters and why hypochlorite is no longer a must use ingredient.

Objective: Chlorinated species such as molecular chlorine, hypochlorous acid, and sodium hypochlorite all have antimicrobial properties, yet these differ in the cellular response they eli...