Zachariah Thomas, DPM, AACFAS

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Pertinent Insights On Preventing Injuries On Tennis Court Surfaces

03/03/2017

This author provides a guide to preventing unnecessary tennis injuries caused by inappropriate shoe selection on the sport’s three most common surfaces.

This author provides a guide to...

03/03/2017

Podiatry Today

Rapid Antidepressant Effects and MADRS Item Improvements With AXS-05 (Dextromethorphan-Bupropion), an Oral NMDA Receptor Antagonist, in Major Depressive Disorder: Results from Two Randomized, Double-Blind, Controlled Trials

Abstract: Background: AXS-05 (dextromethorphan-bupropion) is a novel, oral, investigational, NMDA receptor antagonist with multimodal activity being developed for MDD. The dextromethorpha...

Zachariah Thomas , DPM, AACFAS;

William Olsufka , PharmD;

01/19/2023

AXS-05 (Dextromethorphan-Bupropion) Improves Depressive Symptoms and Functioning in Patients with One Prior Treatment Failure: Results from the EVOLVE Long-Term, Open-Label Study

Abstract: Background: In STAR*D, following non-remission with an SSRI, remission rates for second line treatments were ~ 25% regardless of the switch strategy employed. Antidepressants ...

Matthew J. Baker , PharmD;

Zachariah Thomas , DPM, AACFAS;

01/19/2023

Improvement in Anxiety Symptoms in Depressed Patients Treated with AXS-05 (Dextromethorphan-Bupropion): Results from the EVOLVE Open-label, Long-term Study

Abstract: Background: Innovative therapies to treat individuals with MDD, especially those with comorbid anxiety, are urgently needed. AXS-05 (dextromethorphan HBr 45 mg- bupropion HCl...

Shawn Alter , PhD;

Zachariah Thomas , DPM, AACFAS;

01/19/2023

Impact of AXS-05 (Dextromethorphan-Bupropion), an Oral NMDA Receptor Antagonist, on Anhedonic Symptoms in Major Depressive Disorder

Abstract: Background: Treatments for MDD that can improve both overall depressive and anhedonic symptoms are urgently needed. AXS-05 (dextromethorphan-bupropion) is a novel, oral, inv...

Zachariah Thomas , DPM, AACFAS;

01/19/2023