Jed Black, MD

Development of JZP-258, a Low-Sodium Formulation of Oxybate for the Treatment of Cataplexy and Excessive Daytime Sleepiness in Narcolepsy

Narcolepsy is a lifelong neurologic disorder characterized by excessive daytime sleepiness (EDS), cataplexy, disrupted nighttime sleep (DNS), sleep-related hallucinations, and sleep paral...

Gunjan Junnarkar , PhD;

Judith Profant , PhD, MS;

Jed Black , MD;

Teresa Steininger , PhD;

Roman Skowronski , MD, PhD;

10/08/2020

Misdiagnoses and Comorbidities Among Participants in the Nexus Narcolepsy Registry

Background: Narcolepsy diagnosis can be challenging. Presence of comorbidities and overlapping symptoms between narcolepsy and other conditions may contribute to diagnostic delay and misd...

David Pasta , MS;

Danielle Hyman , PhD;

Kathleen Villa , MS;

Jed Black , MD;

Maurice Ohayon , MD, DSc, PhD;

Michael Thorpy , MD, CHBC;

Michael Williams , PhD;

03/01/2019

Quality of Life, Functional Evaluation, and Work Productivity in Patients With Narcolepsy: Results From a Phase 3 Study of Solriamfetol (JZP-110)

INTRODUCTION: Solriamfetol, a selective dopamine/norepinephrine reuptake inhibitor, significantly decreased excessive sleepiness in a randomized, double-blind, placebo-controlled study of...

Michael Thorpy , MD, CHBC;

Giuseppe Plazzi , MD;

Yves Dauvilliers , MD, PhD;

Colin Shapiro , PhD, FRCPC, MBBCh;

Jed Black , MD;

Geert Mayer , MD;

Helene Emsellem , MD;

Dandan Chen , MD, PhD;

Robert Ryan , MS;

Gert Jan Lammers , PhD, MD;

Chevy Chase , MD;

Lawrence Carter , PhD;

03/01/2019

Long-Term Safety and Efficacy of Sodium Oxybate in Pediatric Patients With Narcolepsy: Evaluation of Depression, Anxiety, and Suicidal Risk

Introduction: Narcolepsy primarily begins in childhood/adolescence. Sodium oxybate (SXB) was evaluated as a treatment for narcolepsy in children/adolescents in a placebo-controlled, rando...

Emmanuel Mignot , MD, PhD;

Michael Strunc , MD;

Judith Profant , PhD, MS;

Y. Grace Wang , MD;

Rupa Parvataneni , MS;

Jed Black , MD;

03/01/2019

Sodium Oxybate Treatment of Narcolepsy in Pediatric Patients: Long-term Efficacy and Safety

Objective: To evaluate the long-term efficacy and safety of sodium oxybate (SXB) treatment for narcolepsy in pediatric patients in a placebo-controlled, randomized-withdrawal study with a...

Carol Rosen , MD;

Chad Ruoff , MD;

Diane Guinta , PhD;

Rupa Parvataneni , MS;

Jed Black , MD;

Emmanuel Mignot , MD, PhD;

Y. Grace Wang , MD;

Giuseppe Plazzi , MD;

Yves Dauvilliers , MD, PhD;

Michel Lecendreux , MD;

03/01/2019

Cardiovascular Burden of Patients Diagnosed With Idiopathic Hypersomnia: Real-World Idiopathic Hypersomnia Total Health Model (CV-RHYTHM)

This study compared the odds of cardiovascular (CV) conditions in patients with idiopathic hypersomnia (IH) versus matched non-IH controls using Merative™ MarketScan® administrative claim...

Jed Black , MD;

10/26/2023

Diagnosed Prevalence of Idiopathic Hypersomnia Among Adults in the United States

Idiopathic hypersomnia (IH) is a rare neurologic disorder characterized by excessive daytime sleepiness, sleep inertia, long and unrefreshing sleep/naps, and cognitive dysfunction. Sympho...

Jed Black , MD;

10/26/2023