Dong Jing Fu, MD, PhD

Effect of Benzodiazepines on Esketamine Nasal Spray for Treating Patients With Major Depressive Disorder With Active Suicidal Ideation and Intent

Aim: To examine potential effects of concomitant benzodiazepines on the safety and efficacy of esketamine nasal spray following first-dose treatment of patients in urgent need of symptom ...

Dong Jing Fu , MD, PhD;

Bettina Diekamp , PhD;

Janssen Cilag ;

Stephane Borentain , MD;

Robert Murray , MSc, MPH;

Kristin Heerlein , MD;

Qiaoyi Zhang , MD, PhD;

Cornelius S. , MD;

Maju Mathews , MD;

10/08/2020

Esketamine Nasal Spray for Rapid Reduction of Major Depressive Disorder Symptoms in Adult Patients at Imminent Risk for Suicide: ASPIRE-1, a Phase 3 Randomized Study

Introduction: ASPIRE-1 is one of two global phase-3 studies in the registration program to evaluate efficacy and safety of esketamine nasal spray (ESK) vs placebo, with comprehensive stan...

Dong Jing Fu , MD, PhD;

Carla M. Canuso , MD;

Dawn F. Ionescu , MD;

Xiang Li , PhD;

Rosanne Lane , MD, MSc, MS;

Pilar Lim , MD, PhD;

David Hough , MD;

Husseini Manji , MD;

Wayne Drevets , MD;

11/22/2019

Esketamine Nasal Spray for Rapid Reduction of Major Depressive Disorder Symptoms in Adult Patients at Imminent Risk for Suicide: ASPIRE-2, a Phase 3 Randomized Study

Introduction: Efficacy and safety of esketamine (ESK) nasal spray were evaluated in ASPIRE-2 (NCT03097133), one of two phase-3 studies in the first global registration program in an under...

Dong Jing Fu , MD, PhD;

Carla M. Canuso , MD;

Dawn F. Ionescu , MD;

Rosanne Lane , MD, MSc, MS;

Pilar Lim , MD, PhD;

David Hough , MD;

Husseini Manji , MD;

Xin Qiu , MS;

Wayne Drevets , MD;

11/22/2019