Colin Shapiro, PhD, FRCPC, MBBCh

Pooled Analysis From 12-Week Randomized, Controlled Studies of Solriamfetol in the Treatment of Excessive Daytime Sleepiness in Participants With Obstructive Sleep Apnea or Narcolepsy

Background: Solriamfetol (formerly JZP-110), a dopamine and norepinephrine reuptake inhibitor, has been approved in the US (SunosiTM) to improve wakefulness in adults with excessive dayti...

Colin Shapiro , PhD, FRCPC, MBBCh;

Michelle Baladi , PhD;

Dandan Chen , MD, PhD;

Helene Emsellem , MD;

Michael Thorpy , MD, CHBC;

Kris Liu , PhD;

Paula Schweitzer , MD, PhD;

Kimberly Babson , PhD;

11/22/2019

Quality of Life, Functional Evaluation, and Work Productivity in Patients With Narcolepsy: Results From a Phase 3 Study of Solriamfetol (JZP-110)

INTRODUCTION: Solriamfetol, a selective dopamine/norepinephrine reuptake inhibitor, significantly decreased excessive sleepiness in a randomized, double-blind, placebo-controlled study of...

Michael Thorpy , MD, CHBC;

Giuseppe Plazzi , MD;

Yves Dauvilliers , MD, PhD;

Colin Shapiro , PhD, FRCPC, MBBCh;

Jed Black , MD;

Geert Mayer , MD;

Helene Emsellem , MD;

Dandan Chen , MD, PhD;

Robert Ryan , MS;

Gert Jan Lammers , PhD, MD;

Chevy Chase , MD;

Lawrence Carter , PhD;

03/01/2019

Long-Term Safety and Maintenance of Efficacy of Solriamfetol (JZP-110) in the Treatment of Excessive Sleepiness in Participants With Narcolepsy or Obstructive Sleep Apnea

INTRODUCTION: Excessive sleepiness (ES) is a prominent symptom of narcolepsy and obstructive sleep apnea (OSA). Solriamfetol, a selective dopamine/norepinephrine reuptake inhibitor, was e...

Colin Shapiro , PhD, FRCPC, MBBCh;

Richard Schwab , MD;

Jean-Louis Pepin , MD;

Jan Hedner , MD;

Mansoor Ahmed , MD;

Nancy Foldvary-Schaefer , DO, MS;

Patrick Strollo , MD;

Geert Mayer , MD;

Kathleen Sarmiento , MD, MPH;

Michelle Baladi , PhD;

Patricia Chandler , MD;

Lawrence Lee , PhD;