Majid Kerolous, PharmD, MPH

Adjunctive Cariprazine in Patients With Major Depressive Disorder: A Post Hoc Analysis of Efficacy and Safety by Background Antidepressant Therapy

In this post hoc analysis, data from a phase 3 trial were used to evaluate adjunctive cariprazine versus adjunctive placebo by background ADT in patients with MDD and inadequate response ...

Majid Kerolous , PharmD, MPH;

10/26/2023

Cariprazine as an Adjunctive Treatment for Major Depressive Disorder: Assessment of Benefit and Risk Using Number Needed to Treat and Number Needed to Harm

The benefit-risk profile of cariprazine is favorable for major depressive disorder adjunctive treatment.

Majid Kerolous , PharmD, MPH;

10/26/2023

Effect of Adjunctive Cariprazine on Symptoms of Anhedonia in Patients with Major Depressive Disorder

Results from this post-hoc analysis suggest adjunctive cariprazine treatment may be effective for improving symptoms of anhedonia in patients with major depressive disorder.

Majid Kerolous , PharmD, MPH;

10/26/2023

Incidence and Characteristics of Akathisia With Adjunctive Cariprazine Treatment in Patients With Major Depressive Disorder

Incidence of akathisia was higher for cariprazine than placebo, with lower incidence observed for patients treated with cariprazine 1.5mg/d+ADT versus 3mg/d+ADT, suggesting dose related e...

Majid Kerolous , PharmD, MPH;

10/26/2023

Efficacy of Cariprazine as Adjunctive Treatment of Major Depressive Disorder in Patients with Anxiety at Baseline: A Post Hoc Analysis of a Randomized Controlled Trial

Abstract: Background: The efficacy of adjunctive cariprazine treatment on depressive symptoms was evaluated in patients with major depressive disorder (MDD) and inadequate response to ant...

Majid Kerolous , PharmD, MPH;

Leslie Citrome , MD;

01/19/2023

Full Range of Clinical Improvement in Depression Symptoms With Adjunctive Cariprazine Treatment in Patients With Major Depressive Disorder: Results From a Randomized Phase 3 Clinical Trial

Abstract: Background: Clinical trial results often report mean changes, though individual responses may be more valuable in clinical practice. This analysis explored the ability of adjunc...

Majid Kerolous , PharmD, MPH;

Leslie Citrome , MD;

01/19/2023