Poster

Antimicrobial effects of a borate-based bioactive glass wound matrix on wound-relevant pathogens

Introduction: Colonization of pathogens in wounds significantly inhibits wound healing and is a major factor in the failure of wounds treated with skin grafts and skin substitutes. Synth...

11/01/2024

Successful effectiveness of a thermo-reversible hydrogel against biofilms with differing dressings

Introduction: Biofilms are a common problem in chronic wounds. A thermo-reversible antimicrobial hydrogel (TRH) containing polyhexanide (PHMB) has previously been shown to be effective ag...

11/01/2024

Retention Processing Preserves Beneficial Stromal and Molecular Components

Introduction: It has been researched and well documented that placental tissue has a plethora of growth factors present. Many of these factors are beneficial when it comes to wound treatm...

11/01/2024

Induction of Diabetic Ulcers through Collagen Glycosylation

Introduction: Diabetic ulcers are a significant complication of diabetes mellitus, commonly attributed to peripheral neuropathy and associated vascular insufficiencies. However, this rev...

11/01/2024

Evaluation of chlorine stabilizing polymer for wound infection control

Introduction: Povidone polymer stabilizes and improves the use of iodine to reduce wound infections, but iodine is a weak oxidizer and not biocompatible. A halohydantoin-based polymer ex...

11/01/2024

Pilot investigation into effect of an antimicrobial dressing on the cell migration effects of decellularized porcine placental extracellular matrix in viable wounded human skin ex vivo

Introduction: Decellularized extracellular matrix (ECM) medical devices can facilitate healing of hard-to-heal wounds by acting as a scaffold. A novel decellularized porcine placental ECM...

11/01/2024

Effects of Collagen Wound Matrix-Micronized on Fibroblast Function and Protease

Introduction: The interplay between fibroblasts and extracellular matrix (ECM) proteins is an important factor in the normal wound healing cascade. Matrix metalloproteinases (MMPs) are ce...

11/01/2024

Harnessing the power of our immune system: the antimicrobial mode of action of nitric oxide

Introduction: The presence of microorganisms, development of biofilm, and local infection play a significant role in the pathogenesis of hard-to-heal wounds. Systemic antimicrobial therap...

11/01/2024

Assessment of the Healing Rate of Artacent Wound Pro, a Dual Layer Amnion Wound Covering Sterilized with a Novel Process

Introduction: Placenta-based scaffolds are known for their regenerative potential in various clinical applications, often requiring terminal sterilization to ensure safety. The choice of ...

11/01/2024

Crosslinked Native Collagen Matrices Containing Polyhexamethylene Biguanide (PHMB) Modulate Matrix Metalloproteinases, Function as Scaffold for Cell Growth, and Inhibit Bacterial Growth In Vitro and In Vivo

Introduction: Collagen-based wound matrices are widely used for treating acute and chronic wounds due to their role in wound management. The addition of an antimicrobial to these matrices...

11/01/2024