TV-46000 is an FDA-approved long-acting subcutaneous antipsychotic (LASCA) formulation of risperidone that has been shown to reduce time to impending relapse in patients with schizophreni...
This poster is part of the requirement in fulfillment of a Doctor of Nursing Practice (DNP) degree at Rutgers University, School of Nursing. The purpose of the project is to improve the s...
AXS-05 exhibited rapid and sustained improvements in cognitive and physical functioning in individuals with MDD who previously tried one or more prior antidepressants. This study also sho...
Daytime impairment can be assessed by items 4-7 of the 7-item Insomnia Severity Index. Here we report the impact of lemborexant (LEM) versus placebo on shifts in daytime-function-specific...
In GEMINI, AXS-05, an oral NMDA receptor antagonist approved for MDD, showed significantly higher response rates (defined as 50% reduction in QIDS insomnia score) starting at Week 3 throu...
Depression is a prevalent comorbidity associated with migraine, and the bidirectional relationship between the two disorders can negatively impact quality of life (QoL). During the 12-wee...
Adjunctive therapy with atypical antipsychotics is a treatment option for patients diagnosed with major depressive disorder and inadequate response to antidepressant monotherapy. This cla...
This retrospective analysis of administrative claims data compared healthcare resource utilization 6 months before and after initiating a combination of olanzapine and samidorphan (OLZ/SA...
This case report demonstrates a relationship between Olanzapine and hyperventilation. Increased minute ventilation on the ventilator while on olanzapine therapy, lack of other causes of i...
Patients with major depressive disorder often have reduced quality of life. A previous phase 3 trial showed cariprazine adjunctive to antidepressant therapy reduces depressive symptoms in...