BackgroundRAS/RAF mutation status is a major molecular outcome in colorectal cancer (CRC), and these mutations have been suggested as predictive and prognostic biomarkers. Previous report...
BackgroundThe incidence of pancreatic cancer (PC) has been increasing and continues to be associated with a high mortality rate. Surgical resection is the only curative option. About 15% ...
BackgroundColorectal cancer (CRC) is the third most common cancer worldwide, with 1.1 million new cases every year. In Portugal, recent data have shown that colorectal cancer was the most...
BackgroundShort-course radiotherapy (5 x 5 Gy) followed by chemotherapy before total mesorectal excision (TME) decreased the probability of disease-related treatment failure and became th...
BackgroundGastric cancer is a disease with a high mortality rate, even in early stages. The combination of surgery with perioperative systemic treatment with the FLOT regimen, based on fl...
BackgroundSolid cancer patients are at high risk of a more severe course of COVID-19, especially those undergoing active anti-cancer therapy causing immunosuppression. Vaccination is stil...
BackgroundIn metastatic colorectal cancer (mCRC) the choice of treatment should take into account the characteristics of the tumor and the patient, as well as its efficacy and tolerabilit...
BackgroundMetachronous recurrence incidences and risk factors following endoscopic submucosal dissection (ESD) for gastric adenocarcinoma and dysplasias were investigated.
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BackgroundTrifluridine/tipiracil (TAS102) has been shown to improve survival in later lines of treatment of metastatic colorectal cancer patients, irrespective of RAS status. This study a...
BackgroundVascular endothelial growth factor (VEGF) is a crucial regulator of physiological and pathological angiogenesis. Increased VEGF expression has been linked with inappropriate VEG...