Nader Mankerious, MD1*; Katharina Mayer, MD1*; Senta M. Gewalt, MD1; Sandra M. Helde, MD1,2; Tareq Ibrahim, MD3; Lorenz Bott-Flügel, MD2; Karl-Ludwig Laugwitz, MD3,4; Heribert Schunkert, MD1,4; Adnan Kastrati, MD1,4; Stefanie Schüpke, MD1,4; for the Instrumental Sealing of ARterial puncture site – CLOSURE device versus manual compression (ISAR-CLOSURE) Trial Investigators