Biofilm

In vivo Detection of Bacteria Within a Biofilm Using a Point-of-care Fluorescence Imaging Device

Abstract Body: Introduction: Biofilm is bacteria that exists within a protective matrix, making it particularly challenging to eradicate through antimicrobial and antibiotic strategies. B...

11/23/2020

Assessment of the Biofilm Disruption Activity of Absorbent Sustained-action Dressing with Povidone Iodine

Abstract Body: Objective: Over 65% of bacterial infections treated in the developed world are known to include biofilms, which are less susceptible to host defences or conventional therap...

11/23/2020

Antibiofilm Efficacy of an Iodine Dressing in Comparison to Other Antibacterial Dressings Against Immature and Mature Biofilms

Abstract Body: Biofilms can form on surfaces, such as medical devices and wounds, leading to infection, inflammation and delayed wound healing. Unlike their planktonic counterparts, biofi...

11/23/2020

Antibiofilm Efficacy of an Iodine Dressing and Comparator Dressings Against a Multispecies Biofilm, Anaerobic Biofilm and Fungal Biofilm

Abstract Body: Although biofilms can be formed by a single species, they are generally multispecies and can comprise of aerobic bacteria, anaerobic bacteria, fungi and yeasts. Biofilms ar...

11/23/2020

Proof of principle: rapidly removing biofilm and necrosis in hard to heal ulcers using a hygroscopic chemical compound.

Introduction: The chronicity of hard-to-heal lesions is caused and sustained by a number of factors, including the development and presence of biofilm, which contributes significantly to ...

11/23/2020

Original Research

Synergistic Effect and Antibiofilm Activity of a Skin and Wound Cleanser

08/01/2020

Ann Beal Salamone

Joseph C. Salamone

Rebecca Erin McMahon

Suprena Poleon

Nina Bionda

Peter D’Arpa

In this study, 3 of the components in a wound cleanser are tested to determine synergy in eradicating biofilms of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in vitro.

In this study, 3 of the...

08/01/2020

Wounds

Current Research

Topical Oxygen Therapy Shifts Microbiome Dynamics in Chronic Diabetic Foot Ulcers

03/03/2020

Paul Hunter

Elisa Greco

Karen Cross

Julie Perry

This study aims to determine the mechanism of action of topical oxygen in diabetic foot ulcers (DFUs) by examining the diversity of bacterial genera present in DFUs treated with topical oxygen.

This study aims to determine the...

03/03/2020

Wounds

Evaluation of the Biofilm Prevention and Disinfection Capabilities of Topical Wound Treatments

There are a number of topical wound coverings that claim to be effective in treating or preventing bacterial infections and biofilms within the wounds. This work has been undertaken to de...

12/09/2019

Detection of Biofilm Extracellular Polymeric Substances After Treatment with Surfactant-Based Wound Gels

In wounds, biofilms form a diverse mix of cellular aggregates and self-producing extracellular polymeric substances (EPS). The development of EPS is important for biofilm establishment, t...

12/06/2019

A Novel Biofilm Disruptive Agent Influences the Wound Healing Process by Altering the Level of Cytokines and Chemokines Within the Wound

Wound healing occurs through specific overlapping steps involving different host cell types and mediated by cytokines and chemokines (C/C) with pleiotropic functions. We previously showed...

12/06/2019