Thomas Roth, PhD

Application of AASM Clinical Significance Thresholds to Once-Nightly Sodium Oxybate for Improvement in Narcolepsy Symptoms

Results from the phase 3 REST-ON trial that demonstrated efficacy/safety of extended-release sodium oxybate (once-nightly sodium oxybate [ON-SXB]; LUMRYZ™) were published after the cutoff...

Thomas Roth , PhD;

10/26/2023

Effects of Oxybate on Sleep, Sleep Architecture, and Disrupted Nighttime Sleep

We summarize clinical data on the effects of oxybates on sleep quality, sleep architecture, and disrupted nighttime sleep (DNS) in patients with narcolepsy. Key data from 4 studies on sod...

Thomas Roth , PhD;

10/26/2023