Poster

Outcomes of phosphorus-32 microparticle intratumoural implantation added to chemotherapy in patients with metastatic pancreatic adenocarcinoma

BackgroundMetastatic pancreatic adenocarcinoma (mPDAC) has a poor prognosis with a 5-year survival rate of 3%. In non-metastatic, unresectable locally advanced pancreatic cancer (LAPC) pa...

06/25/2023

The impact of genomic alterations on response rate and survival outcomes in advanced BTC patients who receive cisplatin/gemcitabine plus durvalumab in clinical practice

BackgroundThe TOPAZ-1 phase III trial reported a survival benefit with the anti-programmed death cell ligand 1 (anti-PD-L1) durvalumab in combination with cisplatin/gemcitabine in patient...

06/25/2023

A single arm phase II trial of capecitabine and erlotinib in patients with advanced hepatocellular carcinoma after first-line failure (CAPER- HCC study)

BackgroundLow dose capecitabine in combination with erlotinib has potential anti-tumor activity with limited toxicity, a cost-effective option for advanced hepatocellular carcinoma (HCC)....

06/25/2023

Proteomic identifies heterogeneity of AFP-negative hepatocellular carcinoma

BackgroundHepatocellular carcinoma (HCC) is the third leading cause of cancer-associated mortality worldwide. Alpha-fetoprotein (AFP) is the most commonly used diagnostic marker for HCC. ...

06/25/2023

Recruitment of gastrointestinal cancer patients via PLATON Network: An interactive precision oncology platform

BackgroundThe success of targeted therapies can be evaluated via clinical trials with a wide range of patient cohorts. On the other hand, patient enrolment is one of the main limiting fac...

Arndt Vogel , MD;

06/25/2023

SOX-2 promotes epithelial-to-mesenchymal transition by modulating SLUG expression in esophageal squamous cells

BackgroundEsophageal cancer is the sixth leading cause of cancer-related deaths worldwide, and majority of these cancers, arises from the squamous cells. Despite multiple therapeutic stra...

06/25/2023

Impact of preoperative radiotherapy on lymph node status in patients with rectal cancer: Experience of the radiotherapy department–EHSO Emir Abdelkader-Oran

BackgroundThe aim of the study was to report the histopathological response rate of lymph nodes in patients operated for rectal adenocarcinoma after preoperative radiotherapy alone or com...

06/25/2023

Gastrointestinal microbiome association with health status in Latvian population reveals significant shifts in gastrointestinal cancer patients at taxonomical and functional level

BackgroundDue to the close physiological relationship between humans and their inhabiting microorganisms, many diseases are believed to be associated with alterations from a “healthy” gut...

06/25/2023

Second-line treatment with modified FOLFIRINOX in patients with pancreatic adenocarcinoma who have failed first-line treatment with gemcitabine and nab-paclitaxel

BackgroundAs new evidence emerges, gemcitabine with nab-paclitaxel is becoming increasingly more popular as first-line chemotherapy for pancreatic cancer due to its efficacy over single a...

06/25/2023

The mechanism of DNA methylation-regulated oncogene SERPINE2 in hepatocellular carcinoma metastasis

BackgroundHepatocellular carcinoma (HCC) is the third leading cause of cancer-related death. Early HCC is mainly resected by surgery, but some patients have recurrence and metastasis with...

06/25/2023