Poster

Low dose nivolumab with TKI in advanced HCC: Real world outcomes from India

BackgroundCheckpoint Inhibitor with bevacizumab is unaffordable for most in India and other LMICs. Low dose nivolumab (LD Nivo) has shown comparable efficacy in other solid tumors such as...

06/25/2023

Sarcopenia predicts outcomes in patients with hepatocellular carcinoma treated with atezolizumab and bevacizumab: A multicenter cohort study

BackgroundThe combination of atezolizumab and bevacizumab (A+B) is now the standard of care for the first-line systemic treatment of unresectable hepatocellular carcinoma (HCC). This stud...

06/25/2023

Rising proportion of young individuals with rectal cancer in Mexico: Analysis in a cancer center

BackgroundRecent trends have identified an increasing number of young individuals with rectal and colon cancers. These individuals, who are younger than 50 years old, in most instances wo...

06/25/2023

Clinicopathological characteristics of patients with colorectal cancer lung metastasis under different conditions

BackgroundAfter liver metastasis, lung is the second most common metastatic target organ of colorectal cancer (CRC). This study aimed to explore the clinicopathological features of lung m...

06/25/2023

Reconsidering the TNM stage in non-metastatic colorectal cancer according to the survival paradox

BackgroundThere was a survival paradox in the AJCC TNM staging manual for colorectal cancer (CRC) - some patients at later stages have a better prognosis than those at earlier stages. We ...

06/25/2023

Noninvasive diagnostic models based on CT scans for differentiating solitary pulmonary metastasis in colorectal cancer patients by artificial intelligence: A multicenter study

BackgroundIndeterminate solitary pulmonary nodules are often encountered on CT scans, and diagnosis of solitary pulmonary metastasis (PM) is important for patients with colorectal cancer ...

06/25/2023

Comparison of clinicopathological and molecular features of two rare entities: Appendiceal carcinoma and small bowel adenocarcinoma

BackgroundAppendiceal Carcinoma (AC) and Small Bowel Adenocarcinoma (SBA) are rare malignancies, accounting for approximately 5% of all gastrointestinal cancers. Due to its rarity, high-q...

06/25/2023

Dihydropyrimidine dehydrogenase deficiency frequency and its impact on 5-fluorouracil (5-FU) based chemotherapy toxicity

Background5-fluorouracil (5-FU) and its prodrug capecitabine are Fluoropyrimidines, widely used in colorectal cancer. The prevention of adverse effects related to severe toxicity of Fluor...

06/25/2023

TLE3-AKR1B1 signaling axis participating in the malignant progression of gastrointestinal stromal tumor by regulating galactose metabolism

BackgroundKIT and / or PDGFRA activation mutation is the initial molecular event of gastrointestinal stromal tumor (GIST), and the molecular mechanism leading to the malignant progression...

X. Yin ;

B. Zhang ;

06/25/2023

Delay in pancreatic cancer diagnosis and treatment: Call to action

BackgroundPancreatic cancer is a disease with high mortality. In most cases, it is diagnosed in advanced stages and median overall survival is less than 12 months. Time to diagnosis and t...

06/25/2023