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First Report Managed Care

News

News
05/22/2026
Rebecca Amrick
The clinical and economic burden of chronic kidney disease (CKD) is increased when combined with comorbidities such as type 2 diabetes and heart failure, highlighting the need for improved policies and procedures to optimize disease...
The clinical and economic burden of chronic kidney disease (CKD) is increased when combined with comorbidities such as type 2 diabetes and heart failure, highlighting the need for improved policies and procedures to optimize disease...
The clinical and economic burden...
05/22/2026
First Report Managed Care
News
05/22/2026
Rebecca Amrick
Pembrolizumab plus chemotherapy demonstrates more clinical efficiency in treating patients with metastatic non–small cell lung cancer (mNSCLC), but prolonged survival leads to higher overall health care costs.
Pembrolizumab plus chemotherapy demonstrates more clinical efficiency in treating patients with metastatic non–small cell lung cancer (mNSCLC), but prolonged survival leads to higher overall health care costs.
Pembrolizumab plus chemotherapy...
05/22/2026
First Report Managed Care
Behind the Bill
05/22/2026
Hannah Musick
A bipartisan bill aims to strengthen enforcement of the No Surprises Act amid growing concerns that some health plans are failing to comply with binding payment decisions in the federal dispute resolution process.
A bipartisan bill aims to strengthen enforcement of the No Surprises Act amid growing concerns that some health plans are failing to comply with binding payment decisions in the federal dispute resolution process.
A bipartisan bill aims to...
05/22/2026
First Report Managed Care
News
05/20/2026
Hannah Musick
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib...
05/20/2026
First Report Managed Care
News
05/20/2026
Rebecca Amrick
A retrospective study found that physician-facility alignment influenced treatment for patients with end-stage kidney disease (ESKD) and had a higher likelihood of promoting home-based therapies such as peritoneal dialysis (PD).
A retrospective study found that physician-facility alignment influenced treatment for patients with end-stage kidney disease (ESKD) and had a higher likelihood of promoting home-based therapies such as peritoneal dialysis (PD).
A retrospective study found that...
05/20/2026
First Report Managed Care
News
05/20/2026
Rebecca Amrick
The tyrosine kinase inhibitor (TKI) ponatinib has demonstrated moderately better patient outcomes than imatinib, but its higher costs may complicate treatment decision-making for patients, payers, and providers when it comes to managing...
The tyrosine kinase inhibitor (TKI) ponatinib has demonstrated moderately better patient outcomes than imatinib, but its higher costs may complicate treatment decision-making for patients, payers, and providers when it comes to managing...
The tyrosine kinase inhibitor...
05/20/2026
First Report Managed Care
News
05/18/2026
Rebecca Amrick
Immediate care for alcohol-associated hepatitis (AH) greatly raises health care costs across outpatient, emergency department (ED), and inpatient settings, reflecting the economic impact of AH severity and its comorbidities.
Immediate care for alcohol-associated hepatitis (AH) greatly raises health care costs across outpatient, emergency department (ED), and inpatient settings, reflecting the economic impact of AH severity and its comorbidities.
Immediate care for...
05/18/2026
First Report Managed Care
News
05/14/2026
Rebecca Amrick
Linvoseltamab outperformed real-world treatment regimens for patients with triple-class exposed (TCE) relapsed or refractory multiple myeloma (RRMM), with higher response rates and more durable outcomes in the LINKER-MM1 trial.
Linvoseltamab outperformed real-world treatment regimens for patients with triple-class exposed (TCE) relapsed or refractory multiple myeloma (RRMM), with higher response rates and more durable outcomes in the LINKER-MM1 trial.
Linvoseltamab outperformed...
05/14/2026
First Report Managed Care
News
05/04/2026
Rebecca Amrick
In a recent study, patients with hypertensive emergencies had similar outcomes in intermediate care (IMC) and intensive care unit (ICU) settings, suggesting IMC units may safely reduce ICU utilization without compromising care.
In a recent study, patients with hypertensive emergencies had similar outcomes in intermediate care (IMC) and intensive care unit (ICU) settings, suggesting IMC units may safely reduce ICU utilization without compromising care.
In a recent study, patients with...
05/04/2026
First Report Managed Care
News
05/04/2026
Hannah Musick
Adjuvant immunotherapies may improve lung cancer outcomes, but high costs and budget impact concerns highlight the need for biomarker-guided use, value-based pricing, and phased adoption.
Adjuvant immunotherapies may improve lung cancer outcomes, but high costs and budget impact concerns highlight the need for biomarker-guided use, value-based pricing, and phased adoption.
Adjuvant immunotherapies may...
05/04/2026
First Report Managed Care

KOL Insights

CO
Interview
04/23/2026
Chandra Y. Osborn, PhD, MPH
A member of our First Report Managed Care Editorial Advisory Board explains why managed care decisions hinge on confidence over speed—and how embedding behavioral science across the care continuum can close adherence gaps, activate patients,...
A member of our First Report Managed Care Editorial Advisory Board explains why managed care decisions hinge on confidence over speed—and how embedding behavioral science across the care continuum can close adherence gaps, activate patients,...
A member of our First Report...
04/23/2026
First Report Managed Care
Advanced Squamous Cell Carcinoma of the Anal Canal
Videos
03/31/2026
Lingbin Meng, MD, PhD
Lingbin Meng, MD, discusses how adding retifanlimab to chemotherapy may reshape frontline treatment for advanced squamous cell carcinoma of the anal canal.
Lingbin Meng, MD, discusses how adding retifanlimab to chemotherapy may reshape frontline treatment for advanced squamous cell carcinoma of the anal canal.
Lingbin Meng, MD, discusses how...
03/31/2026
First Report Managed Care
Al B. Benson, III, MD, FACP, FASCO
Videos
03/31/2026
Al B. Benson, III, MD, FACP, FASCO
Dr Benson reviews the epidemiology and unmet clinical need in advanced squamous cell carcinoma of the anal canal (SCAC) and examines the evolving role of immunotherapy in the first-line setting. He also contextualizes recent regulatory and...
Dr Benson reviews the epidemiology and unmet clinical need in advanced squamous cell carcinoma of the anal canal (SCAC) and examines the evolving role of immunotherapy in the first-line setting. He also contextualizes recent regulatory and...
Dr Benson reviews the...
03/31/2026
First Report Managed Care
Videos
03/30/2026
Andy De, CMO
A guest expert explains why generative AI has largely stalled in health care and argues that agentic AI—focused on automating workflows and driving action—offers a more practical path to measurable ROI, improved clinician productivity, and...
A guest expert explains why generative AI has largely stalled in health care and argues that agentic AI—focused on automating workflows and driving action—offers a more practical path to measurable ROI, improved clinician productivity, and...
A guest expert explains why...
03/30/2026
First Report Managed Care
Regulatory Insights
03/30/2026
Adam Colborn, JD
New federal PBM reforms, heightened scrutiny of health care consolidation, and the expansion of direct-to-consumer drug models are poised to reshape the policy landscape, with uncertain implications for patient costs and market dynamics.
New federal PBM reforms, heightened scrutiny of health care consolidation, and the expansion of direct-to-consumer drug models are poised to reshape the policy landscape, with uncertain implications for patient costs and market dynamics.
New federal PBM reforms,...
03/30/2026
First Report Managed Care
MANAGED CARE Q&A
03/26/2026
Abby Reynolds, PharmD
In this interview, a guest expert explains why emotional readiness—not motivation or access alone—often determines whether patients can successfully initiate and persist on specialty therapies.
In this interview, a guest expert explains why emotional readiness—not motivation or access alone—often determines whether patients can successfully initiate and persist on specialty therapies.
In this interview, a guest...
03/26/2026
First Report Managed Care
PIPELINE PROJECTIONS
03/26/2026
Roy Moore
Roy Moore outlines how a rapidly expanding atopic dermatitis pipeline is intensifying competition, reshaping payer strategies, and raising the bar for new therapies.
Roy Moore outlines how a rapidly expanding atopic dermatitis pipeline is intensifying competition, reshaping payer strategies, and raising the bar for new therapies.
Roy Moore outlines how a rapidly...
03/26/2026
First Report Managed Care
MANAGED CARE Q&A
03/26/2026
Allison Oakes, PhD
A guest expert explains why specialty drugs dominating US spending is forcing payers to rethink benefit design, oncology strategy, and biosimilar adoption to control costs and improve value.
A guest expert explains why specialty drugs dominating US spending is forcing payers to rethink benefit design, oncology strategy, and biosimilar adoption to control costs and improve value.
A guest expert explains why...
03/26/2026
First Report Managed Care
ALH
Videos
03/12/2026
Amanda L. Hernandez, MD, PhD
In the second part of this interview, Amanda Hernandez, MD, PhD, examines the role and limitations of Myasthenia Gravis Activities of Daily Living (MG-ADL)  and other outcome measures in myasthenia gravis, emphasizing the importance of...
In the second part of this interview, Amanda Hernandez, MD, PhD, examines the role and limitations of Myasthenia Gravis Activities of Daily Living (MG-ADL)  and other outcome measures in myasthenia gravis, emphasizing the importance of...
In the second part of this...
03/12/2026
First Report Managed Care
ALH
Videos
03/12/2026
Amanda L. Hernandez, MD, PhD
In this interview, Amanda Hernandez, MD, PhD, discusses the evolving general myasthenia gravis (gMG) treatment landscape, highlighting the shift toward more targeted immunologic therapies, the challenges of step therapy, and the need for...
In this interview, Amanda Hernandez, MD, PhD, discusses the evolving general myasthenia gravis (gMG) treatment landscape, highlighting the shift toward more targeted immunologic therapies, the challenges of step therapy, and the need for...
In this interview, Amanda...
03/12/2026
First Report Managed Care

Issue Features

Infographic
05/21/2026
The infographic summarizes 76-week study data from the phase 3 FIBRONEER-IPF trial to provide additional insights on lung function trends, disease progression, mortality risk, and safety outcomes over time with nerandomilast.
The infographic summarizes 76-week study data from the phase 3 FIBRONEER-IPF trial to provide additional insights on lung function trends, disease progression, mortality risk, and safety outcomes over time with nerandomilast.
The infographic summarizes...
05/21/2026
First Report Managed Care
Sponsored
10/16/2025
JOURNAVX is an oral nonopioid indicated for the treatment of moderate-to-severe acute pain in adults—the first and only oral pain signal inhibitor highly selective for NaV1.81
JOURNAVX is an oral nonopioid indicated for the treatment of moderate-to-severe acute pain in adults—the first and only oral pain signal inhibitor highly selective for NaV1.81
JOURNAVX is an oral nonopioid...
10/16/2025
First Report Managed Care
Infographic
08/06/2025
The infographic summarizes the FIBRONEER-IPF Phase 3 trial results, demonstrating nerandomilast significantly reduced the decline in forced vital capacity (FVC) over 52 weeks compared to placebo. Nerandomilast exhibited a favorable safety...
The infographic summarizes the FIBRONEER-IPF Phase 3 trial results, demonstrating nerandomilast significantly reduced the decline in forced vital capacity (FVC) over 52 weeks compared to placebo. Nerandomilast exhibited a favorable safety...
The infographic summarizes the...
08/06/2025
First Report Managed Care
Feature Story
05/12/2025
Lynn Carroll; Rahul Sharma
Health care organizations will be under increasing financial pressure in 2025 and beyond as they struggle to reduce costs while improving care quality—particularly as actions at the federal level threaten to severely disrupt the industry. Not...
Health care organizations will be under increasing financial pressure in 2025 and beyond as they struggle to reduce costs while improving care quality—particularly as actions at the federal level threaten to severely disrupt the industry. Not...
Health care organizations will...
05/12/2025
First Report Managed Care
Feature Story
05/12/2025
David J. Sand, MD, MBA; Lynn Carroll
Value-based care (VBC) is the future of health care. It is the best approach to improving patient outcomes, reducing costs and addressing overall population health through a focus on prevention, care coordination and overall wellness.
Value-based care (VBC) is the future of health care. It is the best approach to improving patient outcomes, reducing costs and addressing overall population health through a focus on prevention, care coordination and overall wellness.
Value-based care (VBC) is the...
05/12/2025
First Report Managed Care

Interactive Features

PIPELINE PROJECTIONS
03/26/2026
Roy Moore
Roy Moore outlines how a rapidly expanding atopic dermatitis pipeline is intensifying competition, reshaping payer strategies, and raising the bar for new therapies.
Roy Moore outlines how a rapidly expanding atopic dermatitis pipeline is intensifying competition, reshaping payer strategies, and raising the bar for new therapies.
Roy Moore outlines how a rapidly...
03/26/2026
First Report Managed Care
Quiz
11/25/2025
True or False: The transformation of traditional health care call centers into “smart access hubs” relies entirely on artificial intelligence (AI) to manage all patient interactions and scheduling.
True or False: The transformation of traditional health care call centers into “smart access hubs” relies entirely on artificial intelligence (AI) to manage all patient interactions and scheduling.
True or False: The...
11/25/2025
First Report Managed Care