Ellison Suthoff, MBA, BS

Edinburgh Postnatal Depression Scale (EPDS) Total Score Remission and Number Needed to Treat (NNT) Outcomes in a Phase 3, Placebo-Controlled Trial of Zuranolone in Postpartum Depression (PPD)

Background: Zuranolone (SAGE-217) is an investigational, neuroactive steroid and GABAA receptor positive allosteric modulator evaluated in a Phase 3 trial in patients with PPD (NCT0297832...

Kristina Deligiannidis , MD;

Ellison Suthoff , MBA, BS ;

Stephen Kanes , MD, PhD;

Brian Werneburg , PhD;

Ming-Yi Huang , PhD;

Robert Lasser , MD, MBA;

Vijayveer Bonthapally , PhD;

Handan Gunduz-Bruce , MD, MBA;

Sarah Acaster , MSc;

Moshe Fridman , PhD;

10/08/2020

Correlation of HAMD-17 and EPDS Scores in a Phase 3 Trial of Zuranolone: An Oral GABAA Receptor Positive Allosteric Modulator in Postpartum Depression

Background: PPD is a common medical complication during and after pregnancy. Zuranolone (SAGE-217) is an investigational neuroactive steroid and GABAA receptor positive allosteric modulat...

Kristina Deligiannidis , MD;

Stephen Kanes , MD, PhD;

Ming-Yi Huang , PhD;

Robert Lasser , MD, MBA;

Handan Gunduz-Bruce , MD, MBA;

Sarah Acaster , MSc;

Moshe Fridman , PhD;

Ellison Suthoff , MBA, BS ;

Vijayveer Bonthapally , PhD;

Abdul Sankoh , PhD;

Brian Werneburg , PhD;

Sigui Li , MS;

10/08/2020

Number Needed to Treat Analysis of the SAGE-217 Phase 2 Clinical Trial Results in Major Depressive Disorder

Background: SAGE-217 is a novel, positive allosteric modulator of GABA(A) receptors under development in Major Depressive Disorder (MDD). This analysis quantified the number needed to tre...

Ken O'Day , PhD, MPA;

Vijayveer Bonthapally , PhD;

Alix Arnaud , MSc;

Ellison Suthoff , MBA, BS ;

Katie Stenson , MSc;

Brian Werneburg , PhD;

Paul Hodgkins , PhD, MSc;

Jeffrey Jonas , MD;

Kellie Meyer , PharmD, MPH;

11/22/2019

Healthcare Resource Utilization 6 Weeks Post-Diagnosis Among Individuals With Major Depressive Disorder in the United States

Abstract: Background: Although major depressive disorder (MDD) is associated with high economic burden, short-term healthcare resource utilization (HCRU) is poorly understood in patients ...

Ellison Suthoff , MBA, BS ;

01/19/2023

Estimation of Healthcare Cost Savings with Zuranolone in Major Depressive Disorder using Health-related Quality of Life to Predict Healthcare Costs

The Medical Expenditure Panel Survey was used to identify adults with major depressive disorder, to predict the association between health-related quality of life scores and annual health...

Ellison Suthoff , MBA, BS ;

10/26/2023

Humanistic and Economic Burden of Depression in the United States (US)

Objective: This study determined differences in outcomes among respondents with and without a depression diagnosis and across symptom severity in respondents with diagnosed depression. ...

Shaloo Gupta , MS;

Vicky Li , MPH;

Alix Arnaud , MSc;

Ellison Suthoff , MBA, BS ;

10/08/2020